N-(4-Bromophenyl)benzamide

Base Information

• Chemical Name: N-(4-Bromophenyl)benzamide
• CAS No.: 7702-38-7
• Molecular Formula: C13H10BrNO
• Molecular Weight: 276.132
• NSC Number: 408048
• DSSTox Substance ID: DTXSID80227834
• Nikkaji Number: J863.938H
• Wikidata: Q83107667
• ChEMBL ID: CHEMBL2234181
• Mol file: 7702-38-7.mol

Synonyms:N-(4-Bromophenyl)benzamide;7702-38-7;Benzamide, N-(4-bromophenyl)-;Benzanilide, 4'-bromo-;BRN 2104886;N-(4-Bromo-phenyl)benzamide;AI3-30012;4-12-00-01507 (Beilstein Handbook Reference);NSC408048;N-Benzoyl-p-bromanilin;Cambridge id 5172521;SCHEMBL1965784;CHEMBL2234181;N~1~-(4-bromophenyl)benzamide;DTXSID80227834;AMY39851;MFCD00017812;STK009326;AKOS000201731;N-Benzoyl derivative of p-bromoaniline;NSC 408048;NSC-408048;LS-25897;CS-0194269;EN300-15538;A865371;SR-01000197536;SR-01000197536-1;Z27786895;5172-52-1

Chemical Property of N-(4-Bromophenyl)benzamide

Chemical Property:

• Vapor Pressure: 0.00176mmHg at 25°C
• Refractive Index: 1.665
• Boiling Point: 293.1°Cat760mmHg
• Flash Point: 131°C
• Density: 1.496g/cm³
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 274.99458
• Heavy Atom Count: 16
• Complexity: 230

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)Br

Technology Process of N-(4-Bromophenyl)benzamide

There total 75 articles about N-(4-Bromophenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-phenyl benzoyl amide (93-98-1,5705-51-1) → N-(4-bromophenyl)benzamide (7702-38-7)

Guidance literature:

With bromine; calcium bromide; In water; at 25 ℃; for 0.333333h; regioselective reaction;

DOI:10.1039/c1gc15359e

Reference yield: 96.0%

1,4-bromoiodobenzene (589-87-7) + benzamide (55-21-0,27208-38-4) → N-(4-bromophenyl)benzamide (7702-38-7)

Guidance literature:

With aluminum oxide; potassium fluoride; copper(l) iodide; 1,10-Phenanthroline; In toluene; at 110 ℃; for 3h;

DOI:10.1055/s-2004-829099

Reference yield: 95.0%

benzoic acid (65-85-0,8013-63-6) + 4-bromo-aniline (106-40-1) → N-(4-bromophenyl)benzamide (7702-38-7)

Guidance literature:

With covalent organic polymer from p-aminophenol and cyanuric chloride; In 1,4-dioxane; at 20 ℃; for 0.5h;

DOI:10.1039/c9dt03931g

upstream raw materials:

N-phenyl benzoyl amide

Benzophenone oxime

N-bromo-benzanilide

benzoyl chloride

Downstream raw materials:

N-(4-bromophenyl)benzimidoyl chloride

N-(2-nitro-4-bromophenyl)benzamide

3-nitro-benzoic acid-(4-bromo-2,6-dinitro-anilide)

N-(4-bromophenyl)benzothioamide

Refernces

• 1、 Gholipour, Behnam,Liu, Xiao,Rostamnia, Sadegh,Zonouzi, Afsaneh. "Single-pot tandem oxidative/C-H modification amidation process using ultrasmall PdNP-encapsulated porous organosilica nanotubes". . p. 4276 - 4287. Retrieved 2022/02/16.
• 2、 Bode, Moira L.,Fish, Muhammad Q.,Mabel Coyanis, E.,Rashamuse, Thompho J.. "Studies towards the design and synthesis of novel 1,5-diaryl-1h-imidazole-4-carboxylic acids and 1,5-diaryl-1h-imidazole-4-carbohydrazides as host ledgf/p75 and hiv-1 integrase interaction inhibitors". . . Retrieved 2021/10/25.