Decyl(Dimethyl)phosphine Oxide

Base Information

• Chemical Name: Decyl(Dimethyl)phosphine Oxide
• CAS No.: 2190-95-6
• Molecular Formula: C12H27 O P
• Molecular Weight: 218.32
• Hs Code.: 2931900090
• European Community (EC) Number: 623-754-8
• UNII: BQ0G8CN4H9
• DSSTox Substance ID: DTXSID90176309
• Nikkaji Number: J668.502A
• Wikidata: Q27096860
• Metabolomics Workbench ID: 150809
• Mol file: 2190-95-6.mol

Synonyms:APO 10;APO-10;decyl(dimethyl)phosphine oxide;decyldimethylphosphine oxide

Chemical Property of Decyl(Dimethyl)phosphine Oxide

Chemical Property:

• Vapor Pressure: 0.000159mmHg at 25°C
• Boiling Point: 341.4°Cat760mmHg
• Flash Point: 160.3°C
• PSA: 26.88000
• Density: 0.87g/cm³
• LogP: 4.74980
• Storage Temp.: +15C to +30C
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 9
• Exact Mass: 218.179952478
• Heavy Atom Count: 14
• Complexity: 160

Purity/Quality:

99%, ^*data from raw suppliers

APO-10 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCP(=O)(C)C
• Recent ClinicalTrials: A Trial of Neoadjuvant Chemotherapy for Stage II, III Esophageal Squamous Cell Carcinoma
• Uses: APO-10 is a novel non-ionic detergent useful for plasmid DNA isolation.

Technology Process of Decyl(Dimethyl)phosphine Oxide

There total 2 articles about Decyl(Dimethyl)phosphine Oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Iododecane (2050-77-3) + dimethyl phosphine oxide (7211-39-4) → decyldimethylphosphine oxide (2190-95-6)

Guidance literature:

dimethyl phosphine oxide; With sodium hexamethyldisilazane; In tetrahydrofuran; at 22 ℃; for 0.25h; Inert atmosphere; Darkness;

Iododecane; In tetrahydrofuran; at 22 ℃; for 16h; chemoselective reaction; Inert atmosphere; Darkness;

DOI:10.1021/acs.organomet.7b00304

Reference yield:

→ decyldimethylphosphine oxide (2190-95-6)

Guidance literature:

upstream raw materials:

Iododecane

dimethyl phosphine oxide

Refernces