Butyramidine hydrochloride

Base Information

• Chemical Name: Butyramidine hydrochloride
• CAS No.: 3020-81-3
• Molecular Formula: C4H11ClN2
• Molecular Weight: 122.598
• Hs Code.: 2942000000
• European Community (EC) Number: 818-226-0
• UNII: UT97Y99LQU
• DSSTox Substance ID: DTXSID60952591
• NSC Number: 66912
• Mol file: 3020-81-3.mol

Synonyms:butyramidine hydrochloride;3020-81-3;Butyrimidamide hydrochloride;butanimidamide hydrochloride;butanimidamide;hydrochloride;butyramidine HCl;butyramidinium chloride;Butanimidamide, monohydrochloride;BUTYRAMIDINE, HCL;MFCD00054341;NSC-66912;butyramidinehydrochloride;butanamidine hydrochloride;Butyrimidamide HCl;amidinopropane hydrochloride;UT97Y99LQU;Butyramidine, monohydrochloride;SCHEMBL1886843;AMY2389;DTXSID60952591;STYCVEYASXULRN-UHFFFAOYSA-N;NSC66912;Butanimidamide, hydrochloride (1:1);AKOS015844017;Butanamidine hydrochloride, AldrichCPR;CS-W013544;Butanimidamide--hydrogen chloride (1/1);SY107786;FT-0651942;EN300-55168;A25916;W10324;Z1198394172;2-(Dimethylamino)ethaneimine;N,N-Dimethyl-2-iminoethylamine

Chemical Property of Butyramidine hydrochloride

Chemical Property:

• Appearance/Colour: white powder-like solid
• Vapor Pressure: 6.12E-06mmHg at 25°C
• Melting Point: 94-96oC
• Refractive Index: 1.707
• Boiling Point: 117.2 °C at 760 mmHg
• Flash Point: 24.7 °C
• PSA: 49.87000
• Density: 1.59g/cm³
• LogP: 2.32450
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: Methanol (Slightly), Water (Slightly)
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 122.0610761
• Heavy Atom Count: 7
• Complexity: 49.5

Purity/Quality:

99.5% ^*data from raw suppliers

ButyramidineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC(=N)N.Cl
• Uses: Butyramidine Hydrochloride is a useful reagent for organic synthesis. It is used as a reagent in the preparation of new derivatives of pyrimidines.

Technology Process of Butyramidine hydrochloride

There total 4 articles about Butyramidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethyl butyrimidate hydrochloride (2208-08-4) → butylamidine hydrochloride (3020-81-3)

Guidance literature:

With ammonia; In ethanol; at -70 ℃;

DOI:10.3987/COM-05-10525

Reference yield:

propyl cyanide (109-74-0) → butylamidine hydrochloride (3020-81-3)

Guidance literature:

propyl cyanide; With trimethylaluminum; ammonium chloride; In toluene; at 80 ℃;

With silica gel; In chloroform; toluene; for 0.166667h;

DOI:10.3987/COM-05-10525

Reference yield:

→ butylamidine hydrochloride (3020-81-3)

Guidance literature:

With ethanol; ammonia;

upstream raw materials:

propyl cyanide

ethyl butyrimidate hydrochloride

Downstream raw materials:

2-propyl-1H-pyrimidine-4,6-dione

N,N,N'-Trichlor-butyramidin

2-n-Propyl-4-hydroxymethylimidazole

5-phenyl-2-propyl-1H-imidazole

Refernces

• 1、 Opitz, Andreas,Sulger, Werner,Daltrozzo, Ewald,Koch, Rainer. "'Green' synthesis of 2-substituted 6-hydroxy-[3H]-pyrimidin-4-ones and 4,6-dichloropyrimidines: Improved strategies and mechanistic study". . p. 814 - 824. Retrieved 2015/05/20.
• 2、 Cabaj, Joanna,Doskocz, Jacek,Soloducho, Jadwiga,Chyla, Antoni. "Convenient synthesis and physicochemical profile of new derivatives of pyrimidine". . p. 137 - 149. Retrieved 2007/10/03.