(DIPHENYLPHOSPHORYL)METHANOL

Base Information

• Chemical Name: (DIPHENYLPHOSPHORYL)METHANOL
• CAS No.: 884-74-2
• Molecular Formula: C13H13O2P
• Molecular Weight: 232.219
• Hs Code.: 2931499090
• Mol file: 884-74-2.mol

Synonyms:(diphenylphosphoroso)methanol;Methanol, (diphenylphosphinyl)-;(hydroxymethyl)diphenylphosphane oxide;(hydroxymethyl)diphenylphosphine oxide;(Diphenylphosphoryl)methanol;Methanol,(diphenylphosphinyl);diphenyl(hydroxymethyl)phosphine oxide;

Chemical Property of (DIPHENYLPHOSPHORYL)METHANOL

Chemical Property:

• Melting Point: 136-137 °C
• Boiling Point: 354.7±25.0 °C(Predicted)
• PKA: 13.41±0.10(Predicted)
• PSA: 47.11000
• Density: 1.21±0.1 g/cm3(Predicted)
• LogP: 1.95030

Purity/Quality:

95% ^*data from raw suppliers

(Diphenylphosphoryl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (DIPHENYLPHOSPHORYL)METHANOL

There total 11 articles about (DIPHENYLPHOSPHORYL)METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

diphenylphosphinomethanol (5958-44-1) → (diphenylphosphinoyl)methanol (884-74-2)

Guidance literature:

With dihydrogen peroxide; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.jorganchem.2007.11.018

Reference yield: 96.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + Diphenylphosphine oxide (4559-70-0) → (diphenylphosphinoyl)methanol (884-74-2)

Guidance literature:

With potassium hydroxide; In water; dimethyl sulfoxide; at 40 - 60 ℃; for 1h;

Reference yield: 95.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + diphenylphosphine oxide (24630-80-6) → (diphenylphosphinoyl)methanol (884-74-2)

Guidance literature:

With potassium hydroxide; In benzene; at 30 - 35 ℃; for 1h;

upstream raw materials:

formaldehyd

Diphenylphosphine oxide

diphenylphosphane

chloro-diphenylphosphine

Downstream raw materials:

1,2-bis(diphenylphosphinoyl)ethane

(thiobis(methylene))bis(diphenylphosphine oxide)

(diphenylphosphinoyl)methyl(cyclopentylidenemethyl)sulfide

(diphenylphosphinoyl)methyl(cyclohexylidenemethyl)sulfide

Refernces

• 1、 Dilelio, Marina Cardoso,Iglesias, Bernardo Almeida,Kaufman, Teodoro S.,Silveira, Claudio C.. "Synthesis and evaluation of photophysical and electrochemical properties of vinyl chalcogenide derivatives of phenothiazines". . . Retrieved 2021/12/07.
• 2、 Boltje, Thomas J.,De Kleijne, Frank F. J.,Moons, Sam J.,White, Paul B.. "C-2 auxiliaries for stereoselective glycosylation based on common additive functional groups". . p. 1165 - 1184. Retrieved 2020/02/22.