2,3-Dihydrobenzofuran

Base Information Edit

Chemical Name:2,3-Dihydrobenzofuran
CAS No.:496-16-2
Molecular Formula:C8H8O
Molecular Weight:120.151
Hs Code.:29329995
European Community (EC) Number:207-817-3
UNII:99E861415L
DSSTox Substance ID:DTXSID2022040
Nikkaji Number:J6.091G
Wikidata:Q27159770
Metabolomics Workbench ID:133034
ChEMBL ID:CHEMBL370688
Mol file:496-16-2.mol

Synonyms:2,3-dihydrobenzofuran;coumaran

Suppliers and Price of 2,3-Dihydrobenzofuran

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,3-Dihydrobenzofuran
5g
$ 60.00

TCI Chemical
2,3-Dihydrobenzofuran >98.0%(GC)
25g
$ 150.00

TCI Chemical
2,3-Dihydrobenzofuran >98.0%(GC)
5g
$ 48.00

SynQuest Laboratories
2,3-Dihydrobenzo[b]furan
5 g
$ 16.00

SynQuest Laboratories
2,3-Dihydrobenzo[b]furan
25 g
$ 28.00

SynQuest Laboratories
2,3-Dihydrobenzo[b]furan
100 g
$ 71.00

Sigma-Aldrich
2,3-Dihydrobenzofuran 99%
25g
$ 99.70

Sigma-Aldrich
2,3-Dihydrobenzofuran 99%
5g
$ 54.50

Matrix Scientific
2,3-Dihydrobenzo[b]furan 95+%
25g
$ 51.00

Matrix Scientific
2,3-Dihydrobenzo[b]furan 95+%
100g
$ 130.00

Total 176 raw suppliers

Chemical Property of 2,3-Dihydrobenzofuran Edit

Chemical Property:

Appearance/Colour:colorless to light yellow liquid
Vapor Pressure:0.836mmHg at 25°C
Melting Point:-21 °C
Refractive Index:n20/D 1.549(lit.)
Boiling Point:188.2 °C at 760 mmHg
Flash Point:66.7 °C
PSA：9.23000
Density:1.096 g/cm³
LogP:1.62150
Storage Temp.:Store below +30°C.
Solubility.:alcohol: soluble
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:120.057514874
Heavy Atom Count:9
Complexity:101

Purity/Quality:

99% ^*data from raw suppliers

2,3-Dihydrobenzofuran ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 23-24/25-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1COC2=CC=CC=C21
Uses 2,3-dihydrobenzofuran is widely used in the synthesis of tricyclic compounds and is also an intermediate raw material for the synthesis of some important drugs. It is used in the synthesis of antitumor agents benzofuran sulfonylureas, HIV protease inhibitor amino acid hydroxyethylenesulfonyl, matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, etc.

Technology Process of 2,3-Dihydrobenzofuran

There total 76 articles about 2,3-Dihydrobenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 271-89-6
1-benzofurane

: 496-16-2
2.3-dihydrobenzofuran

Guidance literature:: With methanol; palladium diacetate; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; In dichloromethane; at 25 ℃; for 12h; chemoselective reaction; Sealed tube; Inert atmosphere;
DOI:10.1002/adsc.202000759