3,3,4,4-tetramethyloxolane-2,5-dione

Base Information

• Chemical Name: 3,3,4,4-tetramethyloxolane-2,5-dione
• CAS No.: 35046-68-5
• Molecular Formula: C₈H₁₂O₃
• Molecular Weight: 156.181
• Hs Code.: 2917190090
• Mol file: 35046-68-5.mol

Synonyms:Succinicanhydride, tetramethyl- (6CI,7CI); NSC 92363; Tetramethylsuccinic anhydride

Chemical Property of 3,3,4,4-tetramethyloxolane-2,5-dione

Chemical Property:

• Vapor Pressure: 0.0834mmHg at 25°C
• Boiling Point: 226.1°Cat760mmHg
• Flash Point: 93.2°C
• PSA: 43.37000
• Density: 1.044g/cm³
• LogP: 1.12220

Purity/Quality:

99%min ^*data from raw suppliers

Tetramethylsuccinicanhydride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,3,4,4-tetramethyloxolane-2,5-dione

There total 17 articles about 3,3,4,4-tetramethyloxolane-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

2,2,3,3-tetramethylsuccinimide (3566-61-8) → tetramethylsuccinic anhydride (35046-68-5)

Guidance literature:

With sulfuric acid; for 4h; Heating;

Reference yield:

tetramethyl succinic acid (630-51-3) → tetramethylsuccinic anhydride (35046-68-5)

Guidance literature:

durch Destillation;

Reference yield:

2,2,3,3-tetramethylsuccinonitrile (3333-52-6) → tetramethylsuccinic anhydride (35046-68-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / NaOH / ethanol; H₂O / 5 h / Heating

2: 54 percent / 60percent sulfuric acid / 4 h / Heating

With sodium hydroxide; sulfuric acid; In ethanol; water;

upstream raw materials:

tetramethyl succinic acid

2,2'-azobis(isobutyronitrile)

chloroform

1,2-dimethylene-3,3,4,4-tetramethylcyclobutane

Downstream raw materials:

3,3,4,4-tetramethyl-1-phenyl-pyrrolidine-2,5-dione

2,2,3-trimethyl-3-phenylbutanoic acid

2,2,3,3-tetramethyl-N-phenyl-succinamic acid

N-(2-oxo-9-trityl-2,9-dihydro-1H-purin-6-yl)-2,2,3,3-tetramethylsuccinimide

Refernces

• 1、 Bizilj, Snezna,Kelly, David P.,Serelis, Algirdas K.,Solomon, David H.,White, Kathleen E.. "The Self-Reactions of 1-Methoxycarbonyl-1-methylethyl and Higher Ester Radicals: Combination vs Disproportionation and Oligomeric Products from Secondary Reactions". . p. 1657 - 1673. Retrieved 2007/10/02.