2,6-DINITROBENZONITRILE

Base Information

• Chemical Name: 2,6-DINITROBENZONITRILE
• CAS No.: 35213-00-4
• Molecular Formula: C7H3N3O4
• Molecular Weight: 193.119
• Hs Code.: 2926909090
• Mol file: 35213-00-4.mol

Synonyms:2,6-Dinitrobenzenecarbonitrile;2,6-Dinitrobenzonitrile;

Chemical Property of 2,6-DINITROBENZONITRILE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 147-149°C
• Refractive Index: 1.616
• Boiling Point: 391.4 °C at 760 mmHg
• Flash Point: 190.5 °C
• PSA: 115.43000
• Density: 1.55 g/cm³
• LogP: 2.42108

Purity/Quality:

99% ^*data from raw suppliers

2,6-Dinitrobenzonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Hazard Codes: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Statements: 20/21/22
• Safety Statements: 22-36/37

MSDS Files:

Useful:

Technology Process of 2,6-DINITROBENZONITRILE

There total 13 articles about 2,6-DINITROBENZONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,6-dinitro-benzaldehyde-oxime (108583-52-4) → 2,6-dinitrobenzonitrile (35213-00-4)

Guidance literature:

With trichloromethyl chloroformate; In acetonitrile; for 0.0833333h;

DOI:10.1055/s-1986-31865

Reference yield: 91.0%

N-(2-hydroxyl-1,1-dimethylethyl) benzamide (19312-05-1) → 2,6-dinitrobenzonitrile (35213-00-4) + N-(1-(2-cyano-3-nitrophenoxy)-2-methylpropan-2-yl)benzamide (1093205-98-1)

Guidance literature:

Reference yield: 82.0%

copper(I) cyanide (544-92-3) + 1-chloro-2,6-dinitrobenzene (606-21-3) → 2,6-dinitrobenzonitrile (35213-00-4)

Guidance literature:

In N,N-dimethyl-formamide; at 140 - 150 ℃; for 2h;

DOI:10.1021/jm00163a067

upstream raw materials:

2,6-dinitroaniline

2,6-dinitro-benzaldehyde-oxime

acetic anhydride

2,6-dinitrobenzoic acid

Downstream raw materials:

2-methoxy-6-nitrobenzonitrile

2,6-diaminobenzonitrile

2-Nitro-6-propylsulfanyl-benzonitrile

2-nitro-6-phenoxybenzonitrile

Refernces

• 1、 Zheng, Guo Zhu,Bhatia, Pramila,Daanen, Jerome,Kolasa, Teodozyj,Patel, Meena,Latshaw, Steven,El Kouhen, Odile F.,Chang, Renjie,Uchic, Marie E.,Miller, Loan,Nakane, Masaki,Lehto, Sonya G.,Honore, Marie P.,Moreland, Robert B.,Brioni, Jorge D.,Stewart, Andrew O.. "Structure-activity relationship of triazafluorenone derivatives as potent and selective mGluR1 antagonists". . p. 7374 - 7388. Retrieved 2007/10/03.
• 2、 Mai, Khuong,Path, Ghanshyam. "Trichloromethyl Carbonochloridate: A Dehydrating Reagent for the Preparation of Nitriles from Aldoximes". . p. 1037 - 1038. Retrieved 2007/10/02.