Technology Process of 2-((4-Nitrophenyl)thio)isoindoline-1,3-dione
There total 4 articles about 2-((4-Nitrophenyl)thio)isoindoline-1,3-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
phthalimide; para-nitrobenzenethiol;
With
pyridine;
In
acetonitrile;
With
bromine;
In
acetonitrile;
DOI:10.1080/10426507.2011.561457
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sulfuryl dichloride; pyridine / dichloromethane / 48 h / 20 °C / Inert atmosphere; Schlenk technique
2.1: magnesium; lithium chloride; iodine / tetrahydrofuran / 2.5 h / 55 °C / Inert atmosphere; Schlenk technique
2.2: 1 h / 0 - 25 °C / Inert atmosphere; Schlenk technique
2.3: 0.83 h / 0 - 25 °C / Inert atmosphere; Schlenk technique
With
pyridine; sulfuryl dichloride; iodine; magnesium; lithium chloride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1002/anie.202009699
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: disulfur dichloride; triethylamine / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
2.1: sulfuryl dichloride; pyridine / dichloromethane / 48 h / 20 °C / Inert atmosphere; Schlenk technique
3.1: magnesium; lithium chloride; iodine / tetrahydrofuran / 2.5 h / 55 °C / Inert atmosphere; Schlenk technique
3.2: 1 h / 0 - 25 °C / Inert atmosphere; Schlenk technique
3.3: 0.83 h / 0 - 25 °C / Inert atmosphere; Schlenk technique
With
pyridine; disulfur dichloride; sulfuryl dichloride; iodine; magnesium; triethylamine; lithium chloride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1002/anie.202009699