1,3-Propanedicarboxamide

Base Information

• Chemical Name: 1,3-Propanedicarboxamide
• CAS No.: 3424-60-0
• Molecular Formula: C5H10N2O2
• Molecular Weight: 130.147
• Hs Code.: 2924199090
• Mol file: 3424-60-0.mol

Synonyms:Glutarsaeure-diamid;propane-1,3-biscarboxamide;GLUTARAMIDE;Pentandiamid;Glutaric acid diamide;1,3-Propanedicarboxamide;Glutarodiamide;

Chemical Property of 1,3-Propanedicarboxamide

Chemical Property:

• Vapor Pressure: 2.92E-09mmHg at 25°C
• Boiling Point: 476.9°Cat760mmHg
• Flash Point: 242.2°C
• PSA: 86.18000
• Density: 1.155g/cm³
• LogP: 0.52790
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

Pentanediamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-Propanedicarboxamide

There total 13 articles about 1,3-Propanedicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

Glutaronitrile (544-13-8) → pentanediamide (3424-60-0)

Guidance literature:

Glutaronitrile; With acetamide; acetic acid; at 50 ℃; for 0.5h; under 760.051 Torr;

With tetrakis(acetonitrile)palladium(II) tetrafluoroborate; at 50 ℃; for 2h; under 1 - 3 Torr; Reagent/catalyst; Pressure;

DOI:10.1055/s-0039-1690026

Reference yield: 28.0%

Glutaronitrile (544-13-8) → 4-cyanobutanamide (53897-27-1) + pentanediamide (3424-60-0)

Guidance literature:

With sodium hydroxide; tricyclohexylphosphine; {Rh(OMe)(cod)}2; In isopropyl alcohol; at 25 ℃; for 48h;

DOI:10.1002/anie.200800366

Reference yield:

→ pentanediamide (3424-60-0)

Guidance literature:

With ammonia; at 175 ℃; under 73550.8 - 110326 Torr;

upstream raw materials:

glutarimide

Diethyl glutarate

N,N'-bis-ethoxycarbonyl-glutaramide

levulinic acid

Downstream raw materials:

piperidine

Trimethylenediamine

1-benzylpiperidine-2,6-dione

Refernces

• 1、 Goto, Akihiro,Endo, Kohei,Saito, Susumu. "RhI-catalyzed hydration of organonitriles under ambient conditions". . p. 3607 - 3609. Retrieved 2008/12/23.