Acetamide, 2-amino-N-hydroxy-

Base Information

• Chemical Name: Acetamide, 2-amino-N-hydroxy-
• CAS No.: 5349-80-4
• Molecular Formula: C14H18N2O
• Molecular Weight: 90.0818
• Hs Code.: 2924199090
• NSC Number: 3841
• UNII: BQZ7J82IFX
• DSSTox Substance ID: DTXSID40201675
• Nikkaji Number: J139.249B
• Wikidata: Q27145299
• ChEMBL ID: CHEMBL216796
• Mol file: 5349-80-4.mol

Synonyms:2-amino-N-hydroxyacetamide;5349-80-4;Acetamide, 2-amino-N-hydroxy-;Glycine hydroxamate;Glycylhydroxamic acid;Glycinehydroxamic acid;2-Amino-N-hydroxy-acetamide;Amino acid hydroxamates glycine hydroxamate;Glycinohydroxamic acid;glycine hydroxamic acid;BQZ7J82IFX;2-Aminoacetohydroxamic acid;AI3-52064;CHEMBL216796;Acetohydroxamic acid, 2-amino-;CHEBI:75426;NSC 3841;NSC-3841;n-hydroxyglycinamide;UNII-BQZ7J82IFX;DTXSID40201675;NSC3841;BDBM50378534;MFCD00243727;(Z)-2-amino-N-hydroxyacetimidic acid;AKOS004903213;AKOS026729110;7G-455S;Acetamide, 2-amino-N-hydroxy- (9CI);CS-0285766;FT-0758891;EN300-862083;Acetohydroxamic acid, 2-amino- (6CI,7CI,8CI);A923414;Q27145299

Chemical Property of Acetamide, 2-amino-N-hydroxy-

Chemical Property:

• Vapor Pressure: 5.34E-08mmHg at 25°C
• Melting Point: 131oC
• Boiling Point: °Cat760mmHg
• PKA: pK1:7.1;pK2:9.1 (25°C)
• Flash Point: °C
• PSA: 78.84000
• Density: 1.311g/cm³
• LogP: -0.00890
• Storage Temp.: −20°C
• XLogP3: -1.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 90.042927438
• Heavy Atom Count: 6
• Complexity: 53.5

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-N-hydroxy-acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(=O)NO)N

Technology Process of Acetamide, 2-amino-N-hydroxy-

There total 3 articles about Acetamide, 2-amino-N-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hydroxylamine (7803-49-8) + glycyl adenylate (35985-26-3) → glycinehydroxamic acid (5349-80-4) + 5'-adenosine monophosphate (61-19-8,24937-83-5,67583-85-1)

Guidance literature:

Reference yield:

H-Gly-NH2 (598-41-4) → glycinehydroxamic acid (5349-80-4) + glycine (56-40-6,18875-39-3,25718-94-9)

Guidance literature:

With hydroxylamine; zinc(II) sulfate; at 50 ℃; pH=6; Further Variations:; Reagents; pH-values; Kinetics;

DOI:10.1039/b211353h

Reference yield:

glycylglycine (556-50-3) → Glycine anhydride (106-57-0) + glycinehydroxamic acid (5349-80-4) + glycylglycine hydroxamic acid (118802-67-8) + glycine (56-40-6,18875-39-3,25718-94-9)

Guidance literature:

With hydroxylamine; zinc(II) sulfate; at 60 ℃; pH=6.8; Further Variations:; Reagents; pH-values; Temperatures; Kinetics;

DOI:10.1039/b211353h

upstream raw materials:

hydroxylamine

glycyl adenylate

glycylglycine

H-Gly-NH₂

Refernces