Benzenamine, N-(methoxymethyl)-2-methyl-

Base Information

• Chemical Name: Benzenamine, N-(methoxymethyl)-2-methyl-
• CAS No.: 88919-92-0
• Molecular Formula: C9H13NO
• Molecular Weight: 151.208
• DSSTox Substance ID: DTXSID10449527
• Nikkaji Number: J689.397J
• Wikidata: Q82269032
• Mol file: 88919-92-0.mol

Synonyms:Benzenamine, N-(methoxymethyl)-2-methyl-;N-(Methoxymethyl)-2-methylaniline;88919-92-0;SCHEMBL14318813;DTXSID10449527

Chemical Property of Benzenamine, N-(methoxymethyl)-2-methyl-

Chemical Property:

• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 151.099714038
• Heavy Atom Count: 11
• Complexity: 106

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1NCOC

Technology Process of Benzenamine, N-(methoxymethyl)-2-methyl-

There total 2 articles about Benzenamine, N-(methoxymethyl)-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + sodium methylate (124-41-4) + o-toluidine (95-53-4) → Methoxymethyl-o-tolyl-amine (88919-92-0)

Guidance literature:

DOI:10.1016/0040-4039(90)80018-H

Reference yield:

methanol (67-56-1) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + o-toluidine (95-53-4) → Methoxymethyl-o-tolyl-amine (88919-92-0)

Guidance literature:

With sodium; Yield given. Multistep reaction; 3.) r.t., 5 h;

DOI:10.1039/P19880001631

Reference yield: 99.0%

Methoxymethyl-o-tolyl-amine (88919-92-0) + o-toluidine (95-53-4) → bis(2-methylphenylamino)methane (54560-77-9)

Guidance literature:

for 10h; under 0.01 Torr; Ambient temperature;

upstream raw materials:

methanol

formaldehyd

o-toluidine

sodium methylate

Downstream raw materials:

3,3'-dimethyl-4,4'-diaminodiphenylmethane

1,3,5-tris(o-tolyl)-hexahydro-s-triazine

2-toluidine

(o-Tolylamino-methyl)-phosphonic acid dimethyl ester

Refernces

• 1、 Barluenga, Jose,Bayon, Ana M.,Campos, Pedro,Asensio, Gregorio,Gonzalez-Nunez, Elena,Molina, Yolanda. "Preparation of N,O-Aminals as Synthetic Equivalents of H2C=NAr and (H2C=NHAr)+ ions: Neutral- and Acid-promoted Transformations". . p. 1631 - 1636. Retrieved 2007/10/02.