4-Pyridylethylmercaptan

Base Information

• Chemical Name: 4-Pyridylethylmercaptan
• CAS No.: 2127-05-1
• Molecular Formula: C7H9 N S
• Molecular Weight: 139.221
• Hs Code.: 2933399090
• Mol file: 2127-05-1.mol

Synonyms:2-(4-Pyridine)ethanethiol;2-(4-Pyridyl)ethane-1-thiol; 2-(4-Pyridyl)ethanethiol;2-(Pyridin-4-yl)ethanethiol; 4-(2-Mercaptoethyl)pyridine

Chemical Property of 4-Pyridylethylmercaptan

Chemical Property:

• Vapor Pressure: 0.041mmHg at 25°C
• Boiling Point: 247.1°Cat760mmHg
• Flash Point: 103.3°C
• PSA: 51.69000
• Density: 1.074g/cm³
• LogP: 1.55390
• Storage Temp.: Amber Vial, Refrigerator, Under Inert Atmosphere

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Pyridylethylmercaptan ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Pyridylethylmercaptan

There total 4 articles about 4-Pyridylethylmercaptan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-vinylpyridine (100-43-6,329041-72-7) → 2-(pyridin-4-yl)ethanethiol (2127-05-1)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; hydrogen sulfide; at 3 - 5 ℃; for 4h; under 6000.6 Torr; Product distribution / selectivity;

Reference yield: 88.9%

4-vinylpyridine (100-43-6,329041-72-7) + thiourea (17356-08-0) → 2-(pyridin-4-yl)ethanethiol (2127-05-1)

Guidance literature:

4-vinylpyridine; thiourea; With sulfuric acid; In water; at 70 ℃; for 6h; Inert atmosphere;

With ammonium hydroxide; In water; toluene; at 20 - 40 ℃; for 5h;

Reference yield: 82.0%

4-(2-mercaptoethyl)pyridinium hydrochloride (6298-11-9) → 2-(pyridin-4-yl)ethanethiol (2127-05-1)

Guidance literature:

With sodium hydroxide; In methanol; at 20 ℃; for 0.5h;

DOI:10.1021/acs.inorgchem.8b02667

upstream raw materials:

4-vinylpyridine

thiourea

4-(2-mercaptoethyl)pyridinium hydrochloride

Downstream raw materials:

2-((2-(pyridin-4-yl)ethyl)thio)ethan-1-ol

(5R,6R)-6-Ethyl-7-oxo-3-(2-pyridin-4-yl-ethylsulfanyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester

diphenylmethyl 7β-[2-(Z)-(2-aminothiazol-4-yl)-2-(trityloxyimino)acetamido]-3-[2-(4-pyridyl)ethylthio]-3-cephem-4-carboxylate

Refernces

• 1、 -. "METHOD FOR PRODUCING BISPHENOL COMPOUND". Paragraph 0138-0142. . Retrieved 2016/11/14.
• 2、 -. "Process for producing pyridylethylthio compound, modified ion exchanger and process for producing the same, and process for producing bisphenol compound". Page/Page column 6. . Retrieved 2008/06/13.