Isolavandulic acid

Base Information

• Chemical Name: Isolavandulic acid
• CAS No.: 3613-55-6
• Molecular Formula: C10H16O2
• Molecular Weight: 168.236
• Mol file: 3613-55-6.mol

Synonyms:Isolavandulinsaeure;2-isopropylidene-5-methyl-4-hexenoic acid;

Chemical Property of Isolavandulic acid

Chemical Property:

• PSA: 37.30000
• LogP: 2.76370

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Isolavandulic acid

There total 3 articles about Isolavandulic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Methylbutenoic acid (541-47-9) + prenyl bromide (870-63-3) → (E)-geranic acid (4698-08-2) + 2-isopropylidene-5-methyl-hex-4-enoic acid (3613-55-6)

Guidance literature:

3-Methylbutenoic acid; With lithium diethylamide; In tetrahydrofuran; at 0 ℃; for 0.5h;

prenyl bromide; In tetrahydrofuran; at 20 ℃; for 1h;

at 200 ℃; for 120h;

DOI:10.1016/S0040-4020(03)01028-7

Reference yield:

2-methyl-3-buten-2-yl 3-methyl-2-butenoate (21634-59-3) → 2-(1-methylethenyl)-5-methyl-4-hexenoic acid (497-67-6) + 2-isopropylidene-5-methyl-hex-4-enoic acid (3613-55-6)

Guidance literature:

With n-butyllithium; 1,1,1,3,3,3-hexamethyl-disilazane; In tetrahydrofuran; hexane; at 40 - 50 ℃; for 8h;

Reference yield:

2-methyl-3-buten-2-yl 3-methyl-2-butenoate (21634-59-3) → 2-(1-methylethenyl)-5-methyl-4-hexenoic acid (497-67-6) + 2-isopropylidene-5-methyl-hex-4-enoic acid (3613-55-6) + (Z)-2-isopropyl-5-methyl-2,4-hexadienoic acid (13377-30-5)

Guidance literature:

With sodium hydride; In toluene; for 23h; Inert atmosphere; Reflux;

upstream raw materials:

3-Methylbutenoic acid

prenyl bromide

2-methyl-3-buten-2-yl 3-methyl-2-butenoate

Refernces

• 1、 -. "PROCESSES FOR PREPARING 2-ISOPROPENYL-5-METHYL-4-HEXENOIC ACID, 2-ISOPROPENYL-5-METHYL-4-HEXEN-1-OL, AND A CARBOXYLATE ESTER THEREOF". Paragraph 0256-0258. . Retrieved 2021/10/22.