2,2-Difluoro-1-phenylethenyl diphenyl phosphate

Base Information

• Chemical Name: 2,2-Difluoro-1-phenylethenyl diphenyl phosphate
• CAS No.: 89264-10-8
• Molecular Formula: C20H15F2O4P
• Molecular Weight: 388.307
• DSSTox Substance ID: DTXSID70531235
• Mol file: 89264-10-8.mol

Synonyms:89264-10-8;2,2-Difluoro-1-phenylethenyl diphenyl phosphate;DTXSID70531235

Chemical Property of 2,2-Difluoro-1-phenylethenyl diphenyl phosphate

Chemical Property:

• XLogP3: 5.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 388.06760228
• Heavy Atom Count: 27
• Complexity: 508

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=C(F)F)OP(=O)(OC2=CC=CC=C2)OC3=CC=CC=C3

Technology Process of 2,2-Difluoro-1-phenylethenyl diphenyl phosphate

There total 1 articles about 2,2-Difluoro-1-phenylethenyl diphenyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

diphenyl hydrogen phosphite (4712-55-4) + 2-chloro-2,2-difluoroacetophenone (384-67-8) → 2,2-difluoro-1-phenylethenyl diphenyl phosphate (89264-10-8)

Guidance literature:

With triethylamine; In tetrahydrofuran; for 24h; Heating;

DOI:10.1016/S0022-1139(00)83035-3

Reference yield: 90.0%

(E)-1-Bromo-2-butene (4784-77-4,39616-19-8,29576-14-5) + 2,2-difluoro-1-phenylethenyl diphenyl phosphate (89264-10-8) → ((E)-1-Difluoromethylene-pent-3-enyl)-benzene (89264-14-2)

Guidance literature:

With copper(l) iodide; n-butyllithium; In tetrahydrofuran; at -60 ℃; for 1h;

DOI:10.1016/S0040-4039(00)94166-2

Reference yield: 88.0%

allyl iodid (556-56-9) + 2,2-difluoro-1-phenylethenyl diphenyl phosphate (89264-10-8) → 1,1-difluoro-2-phenyl-1,4-pentadiene (89264-12-0)

Guidance literature:

With copper(l) iodide; n-butyllithium; In tetrahydrofuran; at -60 ℃; for 1h;

DOI:10.1016/S0040-4039(00)94166-2

upstream raw materials:

diphenyl hydrogen phosphite

2-chloro-2,2-difluoroacetophenone

Downstream raw materials:

C₁₇H₁₄F₂

(1-Difluoromethylene-4-methyl-pent-3-enyl)-benzene

((E)-1-Difluoromethylene-pent-3-enyl)-benzene

1,1-difluoro-2-phenyl-1,4-pentadiene

Refernces

• 1、 Ishihara, Takashi,Yamana, Masayuki,Ando, Teiichi. "ORGANOCUPRATE-INDUCED SUBSTITUTION OF THE ENOL OXYGEN MOIETY IN 2,2-DIFLUORO ENOL PHOSPHATES WITH ALLYL HALIDES: A NOVEL ROUTE TO gem-DIFLUOROOLEFINS FROM CHLORODIFLUOROMETHYL KETONES". . p. 5657 - 5660. Retrieved 2007/10/02.