Dehydroluciferin

Base Information

• Chemical Name: Dehydroluciferin
• CAS No.: 20115-09-7
• Molecular Formula: C11H6N2O3S2
• Molecular Weight: 278.312
• Hs Code.: 2934999090
• Mol file: 20115-09-7.mol

Synonyms:2-(6,7-dimethoxy-[1]isoquinolylmethyl)-4,5-dimethoxy-aniline;6'-Aminopapverin;2-[(6,7-dimethoxyisoquinolyl)methyl]-4,5-dimethoxyphenylamine;2-(6-Hydroxy-benzothiazol-2-yl)-thiazol-4-carbonsaeure;2-(6-hydroxy-benzothiazol-2-yl)-thiazole-4-carboxylic acid;dehydroluciferin;2-(6,7-dimethoxyisoquinolin-1-ylmethyl)-4,5-dimethoxyaniline;2-(6,7-Dimethoxy-[1]isochinolylmethyl)-4,5-dimethoxy-anilin;2-[6'-hydroxy-2'-benzothiazolyl]-thiazole-4-carboxylic acid;2-(6,7-Dimethoxy-isoquinolin-1-ylmethyl)-4,5-dimethoxy-phenylamine;

Chemical Property of Dehydroluciferin

Chemical Property:

• Boiling Point: 595.3±48.0 °C(Predicted)
• PKA: 3.15±0.10(Predicted)
• PSA: 139.79000
• Density: 1.684±0.06 g/cm3(Predicted)
• LogP: 2.82360

Purity/Quality:

97% ^*data from raw suppliers

Dehydroluciferin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Dehydroluciferin

There total 19 articles about Dehydroluciferin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

D-luciferin (2591-17-5) → 2-(6’-hydroxy-2'-benzothiazolyl)-thiazole-4-carboxylic acid (20115-09-7)

Guidance literature:

With oxygen; sodium hydroxide;

DOI:10.1016/j.tet.2013.05.019

Reference yield: 20.0%

2-(6-methoxy-benzothiazol-2-yl)-thiazole-4-carboxylic acid methyl ester (7775-89-5) → 2-(6’-hydroxy-2'-benzothiazolyl)-thiazole-4-carboxylic acid (20115-09-7)

Guidance literature:

With hydrogen bromide; for 1.5h; Reflux;

DOI:10.1016/j.tet.2013.05.019

Reference yield:

2-(6-hydroxy-benzothiazol-2-yl)-thiazole-4-carboxylic acid ethyl ester (36727-09-0) → 2-(6’-hydroxy-2'-benzothiazolyl)-thiazole-4-carboxylic acid (20115-09-7)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 3h;

DOI:10.1016/j.tet.2013.05.019

upstream raw materials:

2-(6-methoxy-benzothiazol-2-yl)-thiazole-4-carboxylic acid methyl ester

D-luciferin

luciferin ethoxyvinyl ester

D-luciferin

Downstream raw materials:

1H-imidazole

Refernces

• 1、 Ciuffreda, Pierangela,Casati, Silvana,Meroni, Giuseppe,Santaniello, Enzo. "A new synthesis of dehydroluciferin [2-(6′-hydroxy-2′- benzothiazolyl)-thiazole-4-carboxylic acid] from 1,4-benzoquinone". . p. 5893 - 5897. Retrieved 2013/07/27.