3-AMINO-2,4,6-TRIBROMOBENZOIC ACID

Base Information

• Chemical Name: 3-AMINO-2,4,6-TRIBROMOBENZOIC ACID
• CAS No.: 6628-84-8
• Molecular Formula: C7H4Br3NO2
• Molecular Weight: 373.826
• Hs Code.: 2922499990
• Mol file: 6628-84-8.mol

Synonyms:2,4,6-Tribromo-3-aminobenzoicacid;3-Amino-2,4,6-tribromobenzoic acid;NSC 59732;

Chemical Property of 3-AMINO-2,4,6-TRIBROMOBENZOIC ACID

Chemical Property:

• Vapor Pressure: 4.15E-11mmHg at 25°C
• Melting Point: 171.5-173.0 °C
• Refractive Index: 1.659
• Boiling Point: 390.4 °C at 760 mmHg
• PKA: 1.43±0.10(Predicted)
• Flash Point: 189.9 °C
• PSA: 63.32000
• Density: 2.446 g/cm³
• LogP: 3.83570

Purity/Quality:

99% ^*data from raw suppliers

3-Amino-2,4,6-tribromobenzoic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3-AMINO-2,4,6-TRIBROMOBENZOIC ACID

There total 2 articles about 3-AMINO-2,4,6-TRIBROMOBENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

meta-aminobenzoic acid (99-05-8,159139-79-4) → 3-amino-2,4,6-tribromobenzoic acid (6628-84-8)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide; sodium bromide; In water; at 15 ℃; for 2h;

DOI:10.1134/S1070427208080314

Reference yield: 86.0%

3-nitrobenzoic acid (121-92-6) → 3-amino-2,4,6-tribromobenzoic acid (6628-84-8)

Guidance literature:

With hydrogen bromide; at 20 ℃; for 4h; Quantum yield; Irradiation;

DOI:10.1016/j.tetlet.2004.08.073

Reference yield: 86.0%

3-amino-2,4,6-tribromobenzoic acid (6628-84-8) → 2,4,6-tribromobenzoic acid (633-12-5)

Guidance literature:

With sulfuric acid; hypophosphorous acid; acetic acid; sodium nitrite; In water; at -5 - 20 ℃; for 12h;

upstream raw materials:

meta-aminobenzoic acid

3-nitrobenzoic acid

Downstream raw materials:

2,4,6-tribromobenzoic acid

2,4,6-tribromoaniline

methylammonium carbonate

2,3,4,6-tetrabromobenzoic acid

Refernces

• 1、 Ghorpade, Prashant Vasantrao,Pethsangave, Dattatray Appasha,Some, Surajit,Shankarling, Ganapati Subray. "Graphene Oxide Promoted Oxidative Bromination of Anilines and Phenols in Water". . p. 7388 - 7397. Retrieved 2018/07/29.
• 2、 Salakhov,Bagmanov,Umaeva,Bagmanova. "Oxidative bromination of aniline and its derivatives". experimental part. p. 1479 - 1481. Retrieved 2009/02/05.