Technology Process of 2H-Cyclopenta[b]furan-2,5-diol,
4-[4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]hexahydro-
There total 6 articles about 2H-Cyclopenta[b]furan-2,5-diol,
4-[4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]hexahydro- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
diisobutylaluminium hydride;
In
tetrahydrofuran; toluene;
at -75 - -40 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: H2SO4
2: MeONa / methanol
3: (COCl)2, NEt3 / dimethylsulfoxide
4: 50percent aq. NaOH, BuNEt3Cl / CH2Cl2
5: (i-Bu)2Al-O-C6H2-(2,6-di-t-Bu,4-Me) / CH2Cl2 / -78 °C
6: (i-Bu)2AlH
With
sodium hydroxide; oxalyl dichloride; sulfuric acid; sodium methylate; triethylbutylammonium chloride; diisobutylaluminium hydride; diisobutyl(2,6-di-tert-butyl-4- methylphenoxy)aluminum; triethylamine;
In
methanol; dichloromethane; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: (COCl)2, NEt3 / dimethylsulfoxide
2: 50percent aq. NaOH, BuNEt3Cl / CH2Cl2
3: (i-Bu)2Al-O-C6H2-(2,6-di-t-Bu,4-Me) / CH2Cl2 / -78 °C
4: (i-Bu)2AlH
With
sodium hydroxide; oxalyl dichloride; triethylbutylammonium chloride; diisobutylaluminium hydride; diisobutyl(2,6-di-tert-butyl-4- methylphenoxy)aluminum; triethylamine;
In
dichloromethane; dimethyl sulfoxide;