4-(4-Methylpiperazino)aniline

Base Information Edit

Chemical Name:4-(4-Methylpiperazino)aniline
CAS No.:16153-81-4
Molecular Formula:C11H17N3
Molecular Weight:191.276
Hs Code.:29349990
European Community (EC) Number:675-543-5
DSSTox Substance ID:DTXSID90353214
Nikkaji Number:J2.530.376H
Wikidata:Q72495565
ChEMBL ID:CHEMBL341473
Mol file:16153-81-4.mol

Synonyms:16153-81-4;4-(4-Methylpiperazino)aniline;4-(4-methylpiperazin-1-yl)aniline;4-(4-Methylpiperazin-1-yl)phenylamine;4-Methyl-1-(4-aminophenyl)piperazine;4-(4-methyl-1-piperazinyl)aniline;1-(4-Aminophenyl)-4-methylpiperazine;4-(4-methylpiperazin-1-yl)benzenamine;Benzenamine, 4-(4-methyl-1-piperazinyl)-;MFCD00172703;4-(4-Methyl-piperazin-1-yl)-phenylamine;CHEMBL341473;MLS000557450;4-(4-Methyl-piperazino)aniline;Oprea1_401071;SCHEMBL56547;cid_737253;F3308-1485;4-(4-Methylpiperazino) aniline;4-(N-methyl-piperizino) aniline;DTXSID90353214;MOZNZNKHRXRLLF-UHFFFAOYSA-N;HMS1728G09;HMS2410O15;BCP24102;CS-M1029;4-(4-methylpiperazine-1-yl)aniline;BDBM50106345;CL1613;STK023618;1-methyl-4-(p-aminophenyl)piperazine;4-(4-methylpiperazin-1-yl)-aniline;4-(4-aminophenyl)-1-methylpiperazine;4-(4-methyl-piperazin-1-yl)-aniline;AKOS000103038;4-(4-methyl-1-piperazinyl)benzenamine;4-(4-methyl-1-piperazinyl)phenylamine;AC-2800;SDCCGMLS-0066262.P001;1-(4-aminophenyl) -4-methylpiperazine;4-(4-methylpiperazin-1-yl)benzeneamine;4-(4-methyl-1-piperazinyl)-benzenamine;4-(4-methylpiperazin-1-yl)-phenylamine;10G-420S;BP-10127;SMR000148366;SY002954;4-(4-methyl-piperazin-1-yl) -phenylamine;A3580;AM20060329;BB 0216416;FT-0616653;M2154;[4-(4-methyl-piperazin-1-yl)-phenyl]-amine;EN300-31965;AG-205/01890046;J-009838;J-513546;Z57345490

Suppliers and Price of 4-(4-Methylpiperazino)aniline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(4-Methylpiperazino)aniline
1g
$ 50.00

TCI Chemical
4-(4-Methyl-1-piperazinyl)aniline >98.0%(GC)
1g
$ 21.00

TCI Chemical
4-(4-Methyl-1-piperazinyl)aniline >98.0%(GC)
5g
$ 64.00

SynChem
4-(4-Methylpiperazin-1-yl)phenylamine 95+%
10 g
$ 105.00

SynChem
4-(4-Methylpiperazin-1-yl)phenylamine 95+%
5 g
$ 60.00

SynChem
4-(4-Methylpiperazin-1-yl)phenylamine 95+%
1 g
$ 25.00

Oakwood
4-(4-Methylpiperazino)aniline 97%
250mg
$ 9.00

Oakwood
4-(4-Methylpiperazino)aniline 97%
5g
$ 30.00

Medical Isotopes, Inc.
4-(4-Methylpiperazino)aniline
10 g
$ 975.00

Matrix Scientific
4-(4-Methylpiperazino)aniline 97%
5g
$ 29.00

Total 128 raw suppliers

Chemical Property of 4-(4-Methylpiperazino)aniline Edit

Chemical Property:

Appearance/Colour:Kind of white to yellow powder
Vapor Pressure:4.09E-05mmHg at 25°C
Melting Point:89-91 °C
Boiling Point:351.5 °C at 760 mmHg
PKA:8.08±0.42(Predicted)
Flash Point:164 °C
PSA：32.50000
Density:1.092 g/cm³
LogP:1.60470
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive.:Air Sensitive
Solubility.:DMSO (Sparingly), Methanol (Slightly)
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:191.142247555
Heavy Atom Count:14
Complexity:167

Purity/Quality:

98%, ^*data from raw suppliers

4-(4-Methylpiperazino)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C
Statements: 34
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)C2=CC=C(C=C2)N
Uses 4-(4-Methylpiperazino)aniline is a reagent in the preparation of benzyloxypyridinone derivative which has c-Met kinase inhibitor properties.

Technology Process of 4-(4-Methylpiperazino)aniline

There total 15 articles about 4-(4-Methylpiperazino)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 16153-81-4
4-(4-Methyl-piperazino)-anilin

Guidance literature:

Reference yield: 100.0%

: 16155-03-6
1-methyl-4-(4-nitrophenyl)piperazine

: 16153-81-4
4-(4-Methyl-piperazino)-anilin

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; at 20 ℃; for 8h; under 2585.74 Torr;
DOI:10.1021/jm050765n

Reference yield: 73.8%

: 109-01-3
1-methyl-piperazine

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 16153-81-4
4-(4-Methyl-piperazino)-anilin

Guidance literature:: 1-methyl-piperazine; 4-Fluoronitrobenzene; With potassium carbonate; In dimethyl sulfoxide; at 40 ℃; for 3h;

With palladium on activated charcoal; hydrogen; In methanol; at 40 ℃; for 1h;