2,2-diphenylpent-4-enoic acid

Base Information

• Chemical Name: 2,2-diphenylpent-4-enoic acid
• CAS No.: 6966-03-6
• Molecular Formula: C17H16O2
• Molecular Weight: 252.313
• Hs Code.: 2916399090
• Mol file: 6966-03-6.mol

Synonyms:2,2-diphenyl-pent-4-enoic acid;2,2-Diphenyl-pent-4-ensaeure;Allyl-diphenyl-essigsaeure;2-allyl-2,2-diphenylacetic acid;2,2-diphenyl-4-pentenoic acid;

Chemical Property of 2,2-diphenylpent-4-enoic acid

Chemical Property:

• Vapor Pressure: 6.87E-05mmHg at 25°C
• Boiling Point: 330°Cat760mmHg
• Flash Point: 167.6°C
• PSA: 37.30000
• Density: 1.119g/cm³
• LogP: 3.63340

Purity/Quality:

99%min ^*data from raw suppliers

2,2-Diphenylpent-4-enoic acid >97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2-diphenylpent-4-enoic acid

There total 15 articles about 2,2-diphenylpent-4-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Allyl acetate (591-87-7) + C20H28O2Si2 (31469-27-9) → 2-allyl-2,2-diphenylacetic acid (6966-03-6)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; for 20h; Heating;

DOI:10.1016/S0022-328X(00)00905-0

Reference yield: 87.0%

2,2-diphenylacetic acid (117-34-0) + allyl bromide (106-95-6) → 2-allyl-2,2-diphenylacetic acid (6966-03-6)

Guidance literature:

2,2-diphenylacetic acid; With lithium diisopropyl amide; In tetrahydrofuran; at 0 - 45 ℃;

allyl bromide; In tetrahydrofuran; at 20 - 45 ℃;

DOI:10.1002/chem.201102476

Reference yield: 86.0%

methyl 2,2-diphenyl-4-pentenoate (107556-96-7) → 2-allyl-2,2-diphenylacetic acid (6966-03-6)

Guidance literature:

With potassium hydroxide; In ethanol; water; for 6h; Reflux; Inert atmosphere;

DOI:10.1021/acs.orglett.7b00657

upstream raw materials:

2,2-diphenyl-pent-4-enenitrile

allyl 2,2-diphenylacetate

2,2-diphenyl-pent-4-enoic acid amide

3-chloroprop-1-ene

Downstream raw materials:

5-(iodomethyl)-3,3-diphenyldihydrofuran-2(3H)-one

7-oxo-6,6-diphenyloxepan-4-yl acetate

5-(2-hydroxyethyl)-3,3-diphenyldihydrofuran-2(3H)-one

4,5-dihydro-3,3-diphenyl-5-<<<(trifluoromethyl)sulfonyl>oxy>methyl>-2(3H)-furanone

Refernces

• 1、 Deng, Xiao-Jun,Liu, Hui-Xia,Zhang, Lu-Wen,Zhang, Guan-Yu,Yu, Zhi-Xiang,He, Wei. "Iodoarene-Catalyzed Oxyamination of Unactivated Alkenes to Synthesize 5-Imino-2-Tetrahydrofuranyl Methanamine Derivatives". . p. 235 - 253. Retrieved 2021/01/09.
• 2、 Deng, Xiaojun,Zhang, Luwen,Liu, Huixia,Bai, Yu,He, Wei. "mCPBA-mediated dioxygenation of unactivated alkenes for the synthesis of 5-imino-2-tetrahydrofuranyl methanol derivatives". . . Retrieved 2020/11/24.