5,5-bis(chloromethyl)-1,3-dioxane

Base Information

• Chemical Name: 5,5-bis(chloromethyl)-1,3-dioxane
• CAS No.: 61729-08-6
• Molecular Formula: C6H10Cl2O2
• Molecular Weight: 185.0484
• Mol file: 61729-08-6.mol

Synonyms:

Chemical Property of 5,5-bis(chloromethyl)-1,3-dioxane

Chemical Property:

• Vapor Pressure: 0.0308mmHg at 25°C
• Boiling Point: 252.4°Cat760mmHg
• Flash Point: 102.8°C
• Density: 1.218g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,5-bis(chloromethyl)-1,3-dioxane

There total 2 articles about 5,5-bis(chloromethyl)-1,3-dioxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

3,3-bis(chloromethyl)oxetane (78-71-7,25323-58-4) → 5,5-dichloromethyl-1,3-dioxane (61729-08-6)

Guidance literature:

With sulfuric acid; In toluene; at 100 ℃; for 4.5h;

Reference yield: 70.0%

3,3-bis(chloromethyl)oxetane (78-71-7,25323-58-4) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → 5,5-dichloromethyl-1,3-dioxane (61729-08-6)

Guidance literature:

With sulfuric acid; In 1,4-dioxane; at 90 - 100 ℃; for 5h;

DOI:10.1134/S1070363214100119

Reference yield: 22.0%

5,5-dichloromethyl-1,3-dioxane (61729-08-6) → 5-iodomethyl-5-chloromethyl-1,3-dioxane (61729-05-3)

Guidance literature:

With sodium iodide; In acetone; at 62 ℃; for 175h;

upstream raw materials:

3,3-bis(chloromethyl)oxetane

formaldehyd

Downstream raw materials:

5-iodomethyl-5-chloromethyl-1,3-dioxane

Refernces

• 1、 Kurmaeva, E. S.,Chalova, O. B.,Chistoedova, G. P.,Lapuka, L. F.,Kiladze, T. K.,et al.. "SYNTHESIS OF IODINE-SUBSTITUTED 1,3-DIOXANES". . p. 119 - 123. Retrieved 2007/10/02.