4-Oxo-2-phenyl-1,4-dihydroquinoline-8-carboxylic acid

Base Information Edit

Chemical Name:4-Oxo-2-phenyl-1,4-dihydroquinoline-8-carboxylic acid
CAS No.:90034-64-3
Molecular Formula:C16H11NO3
Molecular Weight:265.26300
Hs Code.:
DSSTox Substance ID:DTXSID50540320
Wikidata:Q82416292
Mol file:90034-64-3.mol

Synonyms:90034-64-3;4-Oxo-2-phenyl-1,4-dihydroquinoline-8-carboxylic acid;SCHEMBL8809899;DTXSID50540320

Suppliers and Price of 4-Oxo-2-phenyl-1,4-dihydroquinoline-8-carboxylic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Oxo-2-phenyl-1,4-dihydroquinoline-8-carboxylic acid Edit

Chemical Property:

Boiling Point:490.9±45.0 °C(Predicted)
PSA：70.42000
Density:1.347±0.06 g/cm3(Predicted)
LogP:3.30560
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:265.07389321
Heavy Atom Count:20
Complexity:437

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=O)C3=C(N2)C(=CC=C3)C(=O)O

Technology Process of 4-Oxo-2-phenyl-1,4-dihydroquinoline-8-carboxylic acid

There total 5 articles about 4-Oxo-2-phenyl-1,4-dihydroquinoline-8-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 107027-76-9
8-(methoxycarbonyl)-2-phenyl-4(1H)-quinolone

: 90034-64-3
2-phenyl-4(1H)-quinolone-8-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; for 2h; Heating;
DOI:10.1021/jm00122a018

Reference yield: 98.0%

: 90034-64-3
2-phenyl-4(1H)-quinolone-8-carboxylic acid

Guidance literature:

Reference yield:

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 90034-64-3
2-phenyl-4(1H)-quinolone-8-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 39 percent / methanesulfonic acid / benzene / 36 h / Heating

2: 35 percent / various solvent(s) / 255 °C

3: 98 percent / KOH / aq. ethanol / 2 h / Heating

With potassium hydroxide; methanesulfonic acid; In ethanol; benzene;
DOI:10.1021/jm00122a018