Technology Process of Cyclohexanecarboxaldehyde,
2-[2-(2-methoxyphenyl)ethyl]-1,3,3-trimethyl-, trans-
There total 5 articles about Cyclohexanecarboxaldehyde,
2-[2-(2-methoxyphenyl)ethyl]-1,3,3-trimethyl-, trans- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) copper(I)bromide; 2.) aq. HCl / 1.) diethyl ether, THF, 0 deg C; rt, 0.5 h; 2.)THF, reflux, 2 h.
2: 71 percent / triethylaluminium / tetrahydrofuran / 22 h / Ambient temperature
3: 92 percent / boron trifluoride-diethyl ether / CH2Cl2 / 5 h / Ambient temperature
4: 1.) DIBAL; 2.) aq. HCl / 1.) DME, reflux, 2 h; 2.) reflux, 2 h.
5: 60 percent / W1-Raney nickel / acetone / 0.5 h / Ambient temperature
With
hydrogenchloride; W1-Raney nickel; boron trifluoride diethyl etherate; triethylaluminum; diisobutylaluminium hydride; copper(I) bromide;
In
tetrahydrofuran; dichloromethane; acetone;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 71 percent / triethylaluminium / tetrahydrofuran / 22 h / Ambient temperature
2: 92 percent / boron trifluoride-diethyl ether / CH2Cl2 / 5 h / Ambient temperature
3: 1.) DIBAL; 2.) aq. HCl / 1.) DME, reflux, 2 h; 2.) reflux, 2 h.
4: 60 percent / W1-Raney nickel / acetone / 0.5 h / Ambient temperature
With
hydrogenchloride; W1-Raney nickel; boron trifluoride diethyl etherate; triethylaluminum; diisobutylaluminium hydride;
In
tetrahydrofuran; dichloromethane; acetone;
