4-(4-FORMYLPHENOXY)BENZONITRILE 96

Base Information

• Chemical Name: 4-(4-FORMYLPHENOXY)BENZONITRILE 96
• CAS No.: 90178-71-5
• Molecular Formula: C14H9NO2
• Molecular Weight: 223.231
• Hs Code.: 2926909090
• Mol file: 90178-71-5.mol

Synonyms:4-(4-cyano-phenoxy)-benzaldehyde;Benzonitrile,4-(4-formylphenoxy);4-(4-formyl-phenoxy)-benzonitrile;

Chemical Property of 4-(4-FORMYLPHENOXY)BENZONITRILE 96

Chemical Property:

• Vapor Pressure: 2.45E-06mmHg at 25°C
• Melting Point: 88-93oC
• Boiling Point: 391.5oC at 760 mmHg
• Flash Point: 171.3oC
• PSA: 50.09000
• Density: 1.24g/cm3
• LogP: 3.16308

Purity/Quality:

99%min. ^*data from raw suppliers

4-(4-Formylphenoxy)benzonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36-43
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-(4-FORMYLPHENOXY)BENZONITRILE 96

There total 5 articles about 4-(4-FORMYLPHENOXY)BENZONITRILE 96 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

4-fluorobenzonitrile (1194-02-1,143234-87-1) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 4-(4-formylphenoxy)benzonitrile (90178-71-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 150 - 160 ℃; for 3h;

DOI:10.1021/jm901852f

Reference yield: 86.0%

4-fluorobenzaldehyde (459-57-4) + 4-cyanophenol (767-00-0) → 4-(4-formylphenoxy)benzonitrile (90178-71-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; Inert atmosphere;

Reference yield: 72.0%

4-fluorobenzonitrile (1194-02-1,143234-87-1) + 4-cyanophenol (767-00-0) → 4-(4-formylphenoxy)benzonitrile (90178-71-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 155 - 160 ℃; for 3h;

DOI:10.1002/jlac.198419840302

upstream raw materials:

4-fluorobenzaldehyde

4-cyanophenol

4-fluorobenzonitrile

4-hydroxy-benzaldehyde

Downstream raw materials:

(E)-1-(4-cyano-2-nitrophenyl)-2-(4-(4-cyanophenoxy)phenyl)ethene

2-[4-(4-Cyano-phenoxy)-phenyl]-1H-benzoimidazole-5-carboxylic Acid Amide

Refernces

• 1、 -. "Dihydropyrimidine compound and uses of dihydropyrimidine compound in drugs". Paragraph 1162; 1163; 1164; 1165. . Retrieved 2019/01/16.
• 2、 -. "METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS". Paragraph 0283-0284; 0289. . Retrieved 2014/12/09.