2-Amino-3',4'-dimethoxypropiophenone hydrochloride

Base Information

• Chemical Name: 2-Amino-3',4'-dimethoxypropiophenone hydrochloride
• CAS No.: 90253-98-8
• Molecular Formula: C₁₁H₁₅NO₃*ClH
• Molecular Weight: 245.706
• DSSTox Substance ID: DTXSID60512851
• Mol file: 90253-98-8.mol

Synonyms:90253-98-8;2-AMINO-3',4'-DIMETHOXYPROPIOPHENONE HYDROCHLORIDE;2-AMINO-1-(3,4-DIMETHOXYPHENYL)PROPAN-1-ONE HYDROCHLORIDE;2-AMINO-1-(3,4-DIMETHOXYPHENYL)PROPAN-1-ONE HCL;2-amino-1-(3,4-dimethoxyphenyl)propan-1-one;hydrochloride;DTXSID60512851;MFCD04973548;AKOS027339262;CS-0365017;FT-0661741;2-Amino-1-(3,4-dimethoxyphenyl)propan-1-one--hydrogen chloride (1/1)

Chemical Property of 2-Amino-3',4'-dimethoxypropiophenone hydrochloride

Chemical Property:

• Appearance/Colour: Yellow powder
• PSA: 61.55000
• LogP: 2.73600
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 245.0818711
• Heavy Atom Count: 16
• Complexity: 220

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-3?,4?-dimethoxypropiophenoneHCl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)C1=CC(=C(C=C1)OC)OC)N.Cl

Technology Process of 2-Amino-3',4'-dimethoxypropiophenone hydrochloride

There total 1 articles about 2-Amino-3',4'-dimethoxypropiophenone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-Amino-1-(3,4-dimethoxyphenyl)-1-propanon-hydrochlorid (90253-98-8)

Guidance literature:

With hydrogenchloride; acetic acid;

Reference yield: 63.0%

2-Amino-1-(3,4-dimethoxyphenyl)-1-propanon-hydrochlorid (90253-98-8) + acetic anhydride (108-24-7) → 2-(Acetylamino)-1-(3,4-dimethoxyphenyl)-1-propanon (90253-96-6)

Guidance literature:

With pyridine; for 15h;

Reference yield:

2-Amino-1-(3,4-dimethoxyphenyl)-1-propanon-hydrochlorid (90253-98-8) → 7-(3,4-Dimethoxybenzoyl)-5,7-dimethyl-2-phenyl-1H,7H-s-triazolo<1,2-a>-s-triazol-1,3(2H)-dion (90253-93-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 63 percent / pyridine / 15 h

2: 43 percent / PPA / 2.5 h / 80 °C

3: 88 percent / dioxane / 1 h / Ambient temperature

With pyridine; In 1,4-dioxane;

Downstream raw materials:

2-(Acetylamino)-1-(3,4-dimethoxyphenyl)-1-propanon

2-amino-1-(3,4-dimethoxyphenyl)propan-1-ol

5-(3,4-Dimethoxyphenyl)-2,4-dimethyloxazol

7-(3,4-Dimethoxybenzoyl)-5,7-dimethyl-2-phenyl-1H,7H-s-triazolo<1,2-a>-s-triazol-1,3(2H)-dion