Propane, 1,2,3-trimethoxy-

Base Information

• Chemical Name: Propane, 1,2,3-trimethoxy-
• CAS No.: 20637-49-4
• Molecular Formula: C6H14O3
• Molecular Weight: 134.175
• Hs Code.: 2909199090
• DSSTox Substance ID: DTXSID00174674
• Nikkaji Number: J46.519D
• Wikidata: Q63392263
• Mol file: 20637-49-4.mol

Synonyms:1,2,3-Trimethoxypropane;PROPANE, 1,2,3-TRIMETHOXY-;20637-49-4;1,2,3-Trimethyl glycerol triether;1,2,3-trimethoxy-propane;BRN 1736307;Glycerol trimethyl ether;starbld0001318;SCHEMBL51157;1,2,3-Trimethoxypropane #;DTXSID00174674;LS-121100;A901852;Q63392263

Chemical Property of Propane, 1,2,3-trimethoxy-

Chemical Property:

• Vapor Pressure: 6.8mmHg at 25°C
• Refractive Index: 1.4055
• Boiling Point: 143.1°Cat760mmHg
• Flash Point: 42.7°C
• PSA: 27.69000
• Density: 0.912g/cm³
• LogP: 0.29420
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 134.094294304
• Heavy Atom Count: 9
• Complexity: 50.3

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCC(COC)OC

Technology Process of Propane, 1,2,3-trimethoxy-

There total 21 articles about Propane, 1,2,3-trimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl p-toluene sulfonate (80-48-8) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 1,2,3-trimethoxy glycerol ether (20637-49-4)

Guidance literature:

With sodium hydroxide; In water; at 100 ℃; for 3h;

Reference yield: 90.0%

methanol (67-56-1) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 1,2,3-trimethoxy glycerol ether (20637-49-4)

Guidance literature:

amberlyst-15; at 90 ℃; under 750.075 Torr; Product distribution / selectivity;

Reference yield: 79.0%

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) + dimethyl sulfate (77-78-1) → 1,2,3-trimethoxy glycerol ether (20637-49-4)

Guidance literature:

glycerol; With tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide; at 20 ℃; for 0.5h;

dimethyl sulfate; With potassium hydroxide; at 15 - 20 ℃;

DOI:10.1039/c3gc41082j

upstream raw materials:

diazomethane

glycerol

dimethyl sulfate

2-methylglycerol

Refernces

• 1、 Duclos, Marie-Christine,Herbinski, Aurélien,Mora, Anne-Sophie,Métay, Estelle,Lemaire, Marc. "Methylation of Polyols with Trimethylphosphate in the Presence of a Lewis or Br?nsted Acid Catalyst". . p. 547 - 551. Retrieved 2018/01/16.
• 2、 Garca,Pires,Aldea,Lomba,Perales,Giner. "Ecotoxicity studies of glycerol ethers in Vibrio fischeri: checking the environmental impact of glycerol-derived solvents". supporting information. p. 4326 - 4333. Retrieved 2015/08/11.