1,2,5,6,7,8-hexahydrocyclohepta[fg]acenaphthylene

Base Information

• Chemical Name: 1,2,5,6,7,8-hexahydrocyclohepta[fg]acenaphthylene
• CAS No.: 518-02-5
• Molecular Formula: C₁₆H₁₆
• Molecular Weight: 208.303
• Mol file: 518-02-5.mol

Synonyms:Cyclohept[fg]acenaphthylene,1,2,5,6,7,8-hexahydro- (8CI,9CI);1,2,5,6,7,8-Hexahydrocyclohept[fg]acenaphthylene

Chemical Property of 1,2,5,6,7,8-hexahydrocyclohepta[fg]acenaphthylene

Chemical Property:

• Vapor Pressure: 4.97E-06mmHg at 25°C
• Boiling Point: 393°Cat760mmHg
• Flash Point: 210.1°C
• Density: 1.146g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,5,6,7,8-hexahydrocyclohepta[fg]acenaphthylene

There total 11 articles about 1,2,5,6,7,8-hexahydrocyclohepta[fg]acenaphthylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5,6-dibromoacenaphthene (19190-91-1) + buta-1,3-diene (106-99-0,130983-70-9,29406-96-0,9003-17-2) → 1,2,5,6,7,8-hexahydrocyclohepta[fg]acenaphthylene (518-02-5)

Guidance literature:

buta-1,3-diene; With 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; at 20 ℃; for 24h; Schlenk technique; Inert atmosphere;

5,6-dibromoacenaphthene; With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; In tetrahydrofuran; water; at 70 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1021/jacs.1c01826

Reference yield: 52.0%

5,6-dibromoacenaphthene (19190-91-1) + 1,4-bis(bromomagnesium)butane (23708-47-6) → 1,2,5,6,7,8-hexahydrocyclohepta[fg]acenaphthylene (518-02-5)

Guidance literature:

With [1,1'-bis(diphenylphosphino)ferrocene]nickel(II) chloride; In tetrahydrofuran; at 70 ℃; for 10h;

Reference yield:

6,7-dihydrocycloheptacenaphthene-5,8-dione (6345-20-6) → 1,2,5,6,7,8-hexahydrocyclohepta[fg]acenaphthylene (518-02-5)

Guidance literature:

With sodium ethanolate; hydrazine hydrate; at 160 ℃;

DOI:10.1021/ja01350a030

upstream raw materials:

acepleidylene

acepleiadiene

6,7-dihydrocycloheptacenaphthene-5,8-dione

sodium ethanolate

Downstream raw materials:

acepleidylene

Refernces

• 1、 -. "Synthesis method and derivation method of non-benzene type polycyclic aromatic hydrocarbon APD and derivative of non-benzene type polycyclic aromatic hydrocarbon APD". Paragraph 0093-0103. . Retrieved 2021/06/21.