Ethanol, 2-(2-ethoxyethoxy)-, benzoate

Base Information

• Chemical Name: Ethanol, 2-(2-ethoxyethoxy)-, benzoate
• CAS No.: 90327-11-0
• Molecular Formula: C13H18O4
• Molecular Weight: 238.284
• Mol file: 90327-11-0.mol

Synonyms:

Chemical Property of Ethanol, 2-(2-ethoxyethoxy)-, benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanol, 2-(2-ethoxyethoxy)-, benzoate

There total 5 articles about Ethanol, 2-(2-ethoxyethoxy)-, benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) + ethoxyethoxyethanol (111-90-0) → 2-(2-ethoxyethoxy)ethyl benzoate (90327-11-0)

Guidance literature:

With N-methyl-N,N,N-trioctylammonium methylcarbonate; In hexane; for 3h; Molecular sieve; Reflux; Green chemistry;

DOI:10.1039/c7gc03858e

Reference yield: 59.0%

C12H28O3Si + benzaldehyde (100-52-7) → 2-(2-ethoxyethoxy)ethyl benzoate (90327-11-0)

Guidance literature:

With Bromotrichloromethane; In acetonitrile; at 20 ℃; for 26h; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.8b02537

Reference yield: 49.0%

ethoxyethoxyethanol (111-90-0) + benzonitrile (100-47-0) → 2-(2-ethoxyethoxy)ethyl benzoate (90327-11-0)

Guidance literature:

With Bromotrichloromethane; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; at 20 ℃; for 20h; Irradiation; Inert atmosphere;

DOI:10.1039/d0nj00002g

upstream raw materials:

ethoxyethoxyethanol

benzoyl chloride

Benzoyl bromide

2-(2-Ethoxyethoxy)ethyl benzyl ether

Downstream raw materials:

stearyl benzoate

Refernces

• 1、 Hatano, Manabu,Tabata, Yuji,Yoshida, Yurika,Toh, Kohei,Yamashita, Kenji,Ogura, Yoshihiro,Ishihara, Kazuaki. "Metal-free transesterification catalyzed by tetramethylammonium methyl carbonate". supporting information. p. 1193 - 1198. Retrieved 2018/03/27.
• 2、 Pfaff, Dominik,Nemecek, Gregor,Podlech, Joachim. "A lewis acid-promoted pinner reaction". supporting information. p. 1572 - 1577. Retrieved 2013/10/22.