2-BROMOETHYL ISOTHIOCYANATE

Base Information

• Chemical Name: 2-BROMOETHYL ISOTHIOCYANATE
• CAS No.: 1483-41-6
• Molecular Formula: C3H4BrNS
• Molecular Weight: 166.041
• Hs Code.: 2930909090
• Mol file: 1483-41-6.mol

Synonyms:Isothiocyanicacid, 2-bromoethyl ester (8CI);1-Bromo-2-isothiocyanatoethane;2-Bromoethylisothiocyanate;

Chemical Property of 2-BROMOETHYL ISOTHIOCYANATE

Chemical Property:

• Vapor Pressure: 0.26mmHg at 25°C
• Melting Point: 102-108 °C
• Refractive Index: 1.5980
• Boiling Point: 211.8 °C at 760 mmHg
• Flash Point: 81.9 °C
• PSA: 44.45000
• Density: 1.56 g/cm³
• LogP: 1.48410
• Sensitive.: Moisture Sensitive

Purity/Quality:

99%, ^*data from raw suppliers

2-Bromoethyl isothiocyanate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 20/21/22-36/37/38
• Safety Statements: 23-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMOETHYL ISOTHIOCYANATE

There total 1 articles about 2-BROMOETHYL ISOTHIOCYANATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

thiophosgene (463-71-8) + 2-bromoethylamine hydrobromide (2576-47-8) → 1-bromo-2-isothiocyanatoethane (1483-41-6)

Guidance literature:

With triethylamine; In chloroform; for 2h; Ambient temperature;

Reference yield: 87.0%

1-bromo-2-isothiocyanatoethane (1483-41-6) + sodium 4-chlorophenolate (1193-00-6) → 2-(4-chlorophenoxy)thiazoline (91664-76-5)

Guidance literature:

In benzene; for 3h; Heating;

Reference yield: 78.0%

1-bromo-2-isothiocyanatoethane (1483-41-6) + 2-(4-methoxyphenyl)-5-(4-pyridyl)oxazole (151426-99-2) → 1-<4-<(thiocarbonyl)amino>ethyl>-4-<5-(4-methoxyphenyl)-2-oxazolyl> pyridinium bromide

Guidance literature:

In toluene; for 216h; Heating;

upstream raw materials:

thiophosgene

2-bromoethylamine hydrobromide

Downstream raw materials:

N-(2-Chloro-5-trifluoromethyl-phenyl)-N'-(4,5-dihydro-thiazol-2-yl)-hydrazine; hydrobromide

N-(4-Chloro-2-trifluoromethyl-phenyl)-N'-(4,5-dihydro-thiazol-2-yl)-hydrazine; hydrobromide

2-(3,5-bistrifluoromethylphenyl)hydrazinothiazoline hydrobromide

N-(3,5-Dichloro-phenyl)-N'-(4,5-dihydro-thiazol-2-yl)-hydrazine; hydrobromide

Refernces

• 1、 Matsumura, Noboru,Tomura, Masaaki,Chikusa, Hisashi,Mori, Osamu,Inoue, Hiroo. "Synthesis of Novel Tetraazapentalene Derivatives with Fused Cyclic Systems". . p. 965 - 968. Retrieved 2007/10/02.