2,4-Hexadienoyl chloride

Base Information

• Chemical Name: 2,4-Hexadienoyl chloride
• CAS No.: 90554-82-8
• Molecular Formula: C6H7ClO
• Molecular Weight: 130.574
• Mol file: 90554-82-8.mol

Synonyms:

Chemical Property of 2,4-Hexadienoyl chloride

Chemical Property:

• Boiling Point: 180.5±9.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.058±0.06 g/cm3(Predicted)
• LogP: 1.88410

Purity/Quality:

2,4-HexadienoylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,4-Hexadienoyl Chloride is s useful starting material.

Technology Process of 2,4-Hexadienoyl chloride

There total 7 articles about 2,4-Hexadienoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

hexa-2,4-dienoic acid (110-44-1,91751-55-2) → hexa-2,4-dienoyl chloride (90554-82-8)

Guidance literature:

With thionyl chloride; In diethyl ether; for 1h; Heating;

DOI:10.1021/jo0056038

Reference yield: 79.0%

hexa-2,4-dienoic acid (110-44-1,91751-55-2) → (2E)-hexa-2,4-dienoyl chloride (2614-88-2,90554-82-8)

Guidance literature:

With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; for 2h;

DOI:10.1039/b404962d

Reference yield:

(2E)-tert-butyl hexa-2,4-dienoate (53138-73-1,81838-85-9,138605-05-7) → (2E)-hexa-2,4-dienoyl chloride (2614-88-2,90554-82-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 54 percent / TFA / CH₂Cl₂ / 0.5 h / 20 °C

2: 79 percent / oxalyl chloride / CH₂Cl₂; dimethylformamide / 2 h

With oxalyl dichloride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/b404962d

upstream raw materials:

sorbic Acid

hexa-2,4-dienoic acid

(2E)-tert-butyl hexa-2,4-dienoate

Downstream raw materials:

ethyl hexa-2,4-dienoate

hexa-2,4-dienoic acid-(N'-phenyl-hydrazide)

N--4-nitro-3-trifluormethyl-anilin

Aethyl-N-2,4-hexadienoyl-3-chlor-2,6-dimethoxybenzohydroxamat

Refernces

• 1、 Evindar, Ghotas,Batey, Robert A.. "Parallel synthesis of a library of benzoxazoles and benzothiazoles using ligand-accelerated copper-catalyzed cyclizations of ortho-halobenzanilides". . p. 1802 - 1808. Retrieved 2007/10/03.
• 2、 Sriraghavan, Kamaraj,Ramakrishnan, Vayalakkavoor T.. "Photo-Fries and Fries reaction of 5,8-dihydro-1-naphthyl esters". . p. 1791 - 1796. Retrieved 2007/10/03.