Technology Process of N-(2-iodophenyl)-N-methylacetamide
There total 4 articles about N-(2-iodophenyl)-N-methylacetamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
o-iodobenzanilide;
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 0 ℃;
for 0.583333h;
Inert atmosphere;
methyl iodide;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
Inert atmosphere;
DOI:10.1021/acs.orglett.8b02819
- Guidance literature:
-
With
tributylphosphine; sodium iodide; nickel dibromide;
In
1-methyl-pyrrolidin-2-one;
at 190 ℃;
for 7h;
Inert atmosphere;
Molecular sieve;
Sealed tube;
DOI:10.1039/c2cc30956d
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.02 g / pyridine / CH2Cl2 / 12 h / 20 °C
2: 680 mg / NaH / tetrahydrofuran; various solvent(s) / 21 h / 20 °C
With
pyridine; sodium hydride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/ol061858h
