4-[(6-Chloro-1,3-benzoxazol-2-yl)oxy]phenol

Base Information

• Chemical Name: 4-[(6-Chloro-1,3-benzoxazol-2-yl)oxy]phenol
• CAS No.: 70217-01-5
• Molecular Formula: C13H8 Cl N O3
• Molecular Weight: 261.664
• Mol file: 70217-01-5.mol

Synonyms:4-[(6-Chloro-2-benzoxazolyl)oxy]phenol;6-Chloro-2-(4-hydroxyphenoxy)-benzoxazole

Chemical Property of 4-[(6-Chloro-1,3-benzoxazol-2-yl)oxy]phenol

Chemical Property:

• Vapor Pressure: 5.19E-08mmHg at 25°C
• Boiling Point: 430.4oC at 760 mmHg
• Flash Point: 214.1oC
• Density: 1.449g/cm3

Purity/Quality:

98%Min ^*data from raw suppliers

DesethylpropionateFenoxapropP ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Desethylpropionate Fenoxaprop P is an impurity of Fenoxaprop P-Ethyl (F248875), an aryloxyphenoxypropionate compound widely used as an herbicide for control of postemergence annual grasses in crop fields (mostly in rice paddys). Fenoxaprop P-ethyl is routinely used with an agronomic safener in order to minimize the toxic effects of the herbicide on the desired crops.

Technology Process of 4-[(6-Chloro-1,3-benzoxazol-2-yl)oxy]phenol

There total 3 articles about 4-[(6-Chloro-1,3-benzoxazol-2-yl)oxy]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

→ 4-(6-chlorobenzo[d]oxazol-2-yloxy)phenol (70217-01-5)

Guidance literature:

With potassium carbonate; In butanone; for 3h; Reflux;

Reference yield:

2-[4-(6-Chloro-benzooxazol-2-yloxy)-phenoxy]-propionic acid ethyl ester (66441-23-4,113776-20-8,116573-18-3,82110-72-3) → 4-(6-chlorobenzo[d]oxazol-2-yloxy)phenol (70217-01-5) + ethyl 2-{4-[(2-benzoxazolyl)oxy]phenoxy}propanoate (66441-21-2) + 2-Benzoxazolinone (59-49-4) + 6-chlorobenzo[d]oxazol-2(3H)-one (19932-84-4) + 6-hydroxybenzo[d]oxazol-2(3H)-one (78213-03-3) + 4-[(6-hydroxy-2-benzoxazolyl)oxy]phenol (1051401-34-3) + ethyl 2-{4-[(6-hydroxy-2-benzoxazolyl)oxy]phenoxy}propanoate (1051401-33-2) + hydroquinone (123-31-9,8027-02-9) + ethyl 2-(4-hydroxyphenoxy)propanoate (65343-67-1)

Guidance literature:

In water; acetonitrile; Irradiation;

DOI:10.1021/jf801341s

Reference yield:

2,6-dichloro-1,3-benzoxazole (3621-82-7) + hydroquinone (123-31-9,8027-02-9) → 4-(6-chlorobenzo[d]oxazol-2-yloxy)phenol (70217-01-5)

Guidance literature:

With potassium carbonate; In acetonitrile; at 78 - 80 ℃; for 4h;

upstream raw materials:

2-[4-(6-Chloro-benzooxazol-2-yloxy)-phenoxy]-propionic acid ethyl ester

2,6-dichloro-1,3-benzoxazole

hydroquinone

Downstream raw materials:

(-)-ethyl (2S)-2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy]propanoate

fenoxaprop-p-ethyl

Refernces

• 1、 -. "ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF". Paragraph 0094; 0117. . Retrieved 2013/11/19.