etofibrate 2-hydroxymethyl-2-(4-chlorophenoxy)-2-methyl propionate

Base Information

• Chemical Name: etofibrate 2-hydroxymethyl-2-(4-chlorophenoxy)-2-methyl propionate
• CAS No.: 31637-96-4
• Molecular Formula: C12H15 Cl O4
• Molecular Weight: 258.702
• Hs Code.: 2918990090
• Mol file: 31637-96-4.mol

Synonyms:Propionicacid, 2-(p-chlorophenoxy)-2-methyl-, 2-hydroxyethyl ester (8CI)

Chemical Property of etofibrate 2-hydroxymethyl-2-(4-chlorophenoxy)-2-methyl propionate

Chemical Property:

• Vapor Pressure: 1.1E-06mmHg at 25°C
• Boiling Point: 387.1°Cat760mmHg
• Flash Point: 187.9°C
• PSA: 55.76000
• Density: 1.238g/cm³
• LogP: 2.03290

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of etofibrate 2-hydroxymethyl-2-(4-chlorophenoxy)-2-methyl propionate

There total 2 articles about etofibrate 2-hydroxymethyl-2-(4-chlorophenoxy)-2-methyl propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ETOFIBRATE (31637-97-5) → nicotinic acid (59-67-6) + 2-Hydroxyethyl nicotinate (3612-80-4) + Clofibric acid (882-09-7) + 2-(4-Chlorphenoxy)-2-methylpropionsaeure-2-hydroxyethylester (31637-96-4)

Guidance literature:

With propylene glycol; for 0.116667h; pharmacokinetics on intravenous infusion into dogs; other modes of administration, doses and formulations administered;

DOI:10.1002/jps.2600740314

Reference yield:

→ 2-(4-Chlorphenoxy)-2-methylpropionsaeure-2-hydroxyethylester (31637-96-4)

Guidance literature:

2-(p-Chlorphenoxy)-2-methyl-propionsaeure, 1.) NaOH 2.) Ethylenglykolchlorhydrin;

upstream raw materials:

ETOFIBRATE

Refernces