1-PHENYL-ETHANE-1,2-DIAMINE

Base Information

• Chemical Name: 1-PHENYL-ETHANE-1,2-DIAMINE
• CAS No.: 5700-56-1
• Molecular Formula: C8H12 N2
• Molecular Weight: 136.197
• Hs Code.: 2921590090
• Mol file: 5700-56-1.mol

Synonyms:Ethylenediamine,1-phenyl- (6CI,7CI,8CI); 1,2-Diamino-1-phenylethane;1-Phenyl-1,2-diaminoethane; 1-Phenylethane-1,2-diamine; 1-Phenylethylenediamine;Benzenemethanamine, a-(aminomethyl)-

Chemical Property of 1-PHENYL-ETHANE-1,2-DIAMINE

Chemical Property:

• Vapor Pressure: 0.0108mmHg at 25°C
• Boiling Point: 262.6 °C at 760 mmHg
• Flash Point: 132.3 °C
• PSA: 52.04000
• Density: 1.044 g/cm³
• LogP: 2.04570
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

1-Phenyl-1,2-diaminoethane 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-PHENYL-ETHANE-1,2-DIAMINE

There total 34 articles about 1-PHENYL-ETHANE-1,2-DIAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,2-diazido-1-phenylethane (22710-73-2) → 1,2-diaminophenylethane (5700-56-1)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethanol;

DOI:10.1002/anie.201502980

Reference yield: 94.0%

O-methyl-N-(2-nitro-1-phenylethyl)hydroxylamine (889097-59-0) → 1,2-diaminophenylethane (5700-56-1)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; for 4h; under 1758.35 Torr; Product distribution / selectivity;

Reference yield: 85.0%

(Z)-2-azido-1-phenylethanone O-methyloxime (142563-73-3) → 1,2-diaminophenylethane (5700-56-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; Ambient temperature;

upstream raw materials:

3-phenyl-furazan 5-oxide

3-phenyl-furazan 2-oxide

ethanol

anti-phenylglyoxime

Downstream raw materials:

5-phenylpiperazine-2,3-dione

m-phenylpiperazine

4-phenylimidazolidin-2-one

2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid [5-(2-amino-1-phenyl-ethylcarbamoyl)-2-chloro-phenyl]-amide

Refernces

• 1、 Fumagalli, Gabriele,Rabet, Pauline T. G.,Boyd, Scott,Greaney, Michael F.. "Three-Component Azidation of Styrene-Type Double Bonds: Light-Switchable Behavior of a Copper Photoredox Catalyst". supporting information. p. 11481 - 11484. Retrieved 2015/10/14.
• 2、 -. "COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USES AS IDH1 MUTANTS INHIBITORS FOR TREATING CANCERS". Page/Page column 115. . Retrieved 2013/02/28.