PEGANOLE

Base Information

• Chemical Name: PEGANOLE
• CAS No.: 36101-54-9
• Molecular Formula: C₁₁H₁₂N₂O
• Molecular Weight: 188.229
• Hs Code.: 2933990090
• Mol file: 36101-54-9.mol

Synonyms:Peganol

Chemical Property of PEGANOLE

Chemical Property:

• PSA: 35.83000
• LogP: 1.19040

Purity/Quality:

98%Min ^*data from raw suppliers

PEGANOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PEGANOLE

There total 8 articles about PEGANOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

2,3-trimethylene-3,4-dihydroquinazoline hydrochloride (61939-05-7) → peganol (36101-54-9)

Guidance literature:

With potassium permanganate; sulfuric acid; water; for 2h; pH=2 - 3;

DOI:10.1007/s10600-008-9128-6

Reference yield:

deoxypeganine (495-59-0) → peganol (36101-54-9) + deoxyvasicinone (530-53-0)

Guidance literature:

With sodium hydride; In 1,4-dioxane; at 60 - 70 ℃; for 2h;

Reference yield:

peganol-4-oxide → peganol (36101-54-9) + deoxypeganine (495-59-0)

Guidance literature:

With hydrogenchloride; amalgamated zinc; In water; at 20 ℃; for 7h;

DOI:10.1007/BF02234908

upstream raw materials:

2,3-trimethylene-1,2-dihydroquinazolinium picrate

deoxypeganine

2,3-trimethylene-3,4-dihydroquinazoline hydrochloride

o-aminobenzaldehyde

Downstream raw materials:

deoxyvasicinone

Refernces

• 1、 Shakhidoyatov,Mukarramov,Utaeva. "Direction of bromination and nitration of deoxypeganine and its hydrochloride using HPTLC. Synthesis of 6-bromo(nitro)-, 6,8- dinitrodeoxyvasicinones, 6-nitro(bromo)-, 6,8-dinitrodeoxypeganines, and 6H(bromo)peganols". experimental part. p. 625 - 629. Retrieved 2009/04/07.
• 2、 Telezhenetskaya, M. V.,D'yakonov, A. L.. "ALKALOIDS OF Peganum harmala. UNUSUAL REACTION OF PEGANINE AND VASICINONE". . p. 471 - 474. Retrieved 2007/10/02.