N-(2,5-dioxooxolan-3-yl)acetamide

Base Information

• Chemical Name: N-(2,5-dioxooxolan-3-yl)acetamide
• CAS No.: 3397-54-4
• Molecular Formula: C6H7NO4
• Molecular Weight: 157.126
• European Community (EC) Number: 222-259-0
• NSC Number: 128613,128612
• DSSTox Substance ID: DTXSID201264378
• Nikkaji Number: J27.242F
• Mol file: 3397-54-4.mol

Synonyms:N-(2,5-dioxooxolan-3-yl)acetamide;n-(2,5-dioxotetrahydrofuran-3-yl)acetamide;3397-54-4;EINECS 222-259-0;N-Acetyl-DL-aspartic acid-anhydride;(1)-N-(Tetrahydro-2,5-dioxo-3-furyl)acetamide;NSC128612;SCHEMBL10873133;DTXSID201264378;MFCD12545976;NSC128613;AKOS005215250;3-Acetylaminotetrahydrofuran-2,5-dione;NSC 128613;NSC-128612;NSC-128613;CS-0367657;N-(Tetrahydro-2,5-dioxo-3-furanyl)acetamide;F12501;(+-)-N-(tetrahydro-2,5-dioxo-3-furyl)acetamide;A912366

Chemical Property of N-(2,5-dioxooxolan-3-yl)acetamide

Chemical Property:

• Vapor Pressure: 2.39E-09mmHg at 25°C
• Melting Point: 143-144 °C
• Boiling Point: 479.3°Cat760mmHg
• PKA: 13.71±0.20(Predicted)
• Flash Point: 243.7°C
• PSA: 72.47000
• Density: 1.36g/cm³
• LogP: -0.64450
• XLogP3: -1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 157.03750770
• Heavy Atom Count: 11
• Complexity: 223

Purity/Quality:

99% ^*data from raw suppliers

N-(2,5-dioxotetrahydrofuran-3-yl)acetamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1CC(=O)OC1=O

Technology Process of N-(2,5-dioxooxolan-3-yl)acetamide

There total 3 articles about N-(2,5-dioxooxolan-3-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-acetyl-DL-aspartic acid-anhydride (3397-54-4)

Guidance literature:

With acetic anhydride;

DOI:10.1039/jr9530000453

Reference yield:

N-acetyl-DL-aspartic acid (2545-40-6) + acetic anhydride (108-24-7) → N-acetyl-DL-aspartic acid-anhydride (3397-54-4)

Guidance literature:

N-acetyl-aspartic acid;

DOI:10.1039/jr9530000453

Reference yield:

→ N-acetyl-DL-aspartic acid-anhydride (3397-54-4)

Guidance literature:

L-Asparaginsaeure, sd.Ac2O;

DOI:10.1021/ja01481a032

upstream raw materials:

N-acetyl-DL-aspartic acid

acetic anhydride

Downstream raw materials:

N-(N-acetyl-α-aspartyl)-glycine benzylamide