Nsc290426

Base Information

• Chemical Name: Nsc290426
• CAS No.: 17075-39-7
• Molecular Formula: C11H9 Cl
• Molecular Weight: 176.645
• Hs Code.: 2903999090
• Mol file: 17075-39-7.mol

Synonyms:1-Chloro-4-methylnaphthalene;NSC 290426

Chemical Property of Nsc290426

Chemical Property:

• Vapor Pressure: 0.00591mmHg at 25°C
• Boiling Point: 281.9°Cat760mmHg
• Flash Point: 125.5°C
• PSA: 0.00000
• Density: 1.163g/cm³
• LogP: 3.80160

Purity/Quality:

98%min ^*data from raw suppliers

1-Chloro-4-methylnaphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Nsc290426

There total 9 articles about Nsc290426 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-Methylnaphthalene (90-12-0,34475-76-8) → 4-chloro-1-methyl-naphthalene (17075-39-7)

Guidance literature:

With aluminum oxide; copper dichloride; In chlorobenzene; at 130 ℃; for 2h;

DOI:10.1021/jo00244a046

Reference yield: 90.0%

1-bromo-4-methylnaphthalene (6627-78-7) → 4-chloro-1-methyl-naphthalene (17075-39-7)

Guidance literature:

With nickel dichloride; In N,N-dimethyl-formamide; at 170 ℃; Microwave irradiation; Sealed tube; Inert atmosphere;

DOI:10.1021/jacs.1c09889

Reference yield: 62.0%

(4-Chloro-naphthalen-1-ylmethyl)-triphenyl-phosphonium; chloride (97585-94-9) → 4-chloro-1-methyl-naphthalene (17075-39-7) + Triphenylphosphine oxide (791-28-6)

Guidance literature:

With sodium hydroxide; In ethanol; water; Heating;

upstream raw materials:

1-amino-4-methylnaphthalene

1-Methylnaphthalene

1-Nitronaphthalene

methylmagnesium chloride

Downstream raw materials:

4--1-naphthonitrile

4-chloro-2-naphthonitrile

1-bromomethyl-4-chloronaphthalene

4-Methyl-1-naphthoic acid

Refernces

• 1、 Renaud. "". . p. 376,377. Retrieved 1974.
• 2、 Ackermann, Lutz,Jacob, Nicolas,Oliveira, Jo?o C. A.,Wencel-Delord, Joanna,Zaid, Yassir. "Cobalt-Catalyzed Enantioselective C–H Arylation of Indoles". supporting information. p. 798 - 806. Retrieved 2022/02/03.
• 3、 -. "GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE". Paragraph 001016; 001017. . Retrieved 2021/01/22.