Dicyclohexylamine trans-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate

Base Information

• Chemical Name: Dicyclohexylamine trans-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate
• CAS No.: 21157-12-0
• Molecular Formula: C₁₀H₁₇NO₅*C₁₂H₂₃N
• Molecular Weight: 412.57
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID10885163
• Mol file: 21157-12-0.mol

Synonyms:21157-12-0;BOC-HYP-OH DCHA;Dicyclohexylamine trans-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate;Dicyclohexylamine (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate;Boc-trans-4-hydroxy-L-proline dicyclohexylamine sa;Boc-L-4-Hydroxyproline dicyclohexylammonium salt;N-cyclohexylcyclohexanamine;(2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid;(2S)-Dicyclohexylamine trans-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate;SCHEMBL4697635;DTXSID10885163;C22H40N2O5;MFCD00076980;AKOS016003148;FD21753;boc-hydroxyproline dicyclohexylamine salt;AC-32516;DS-18369;CS-0155324;Boc-trans-4-hydroxy-L-proline dicyclohexylamine;(2S)-Dicyclohexylaminetrans-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate

Chemical Property of Dicyclohexylamine trans-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate

Chemical Property:

• Vapor Pressure: 9.99E-08mmHg at 25°C
• Boiling Point: 390.9 °C at 760 mmHg
• Flash Point: 190.2 °C
• PSA: 99.10000
• LogP: 4.01150
• Storage Temp.: Store at 0-5°C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 412.29372238
• Heavy Atom Count: 29
• Complexity: 412

Purity/Quality:

98% ^*data from raw suppliers

Boc-L-4-trans-hydroxyproline dicyclohexylammonium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)N1CC(CC1C(=O)O)O.C1CCC(CC1)NC2CCCCC2
• Isomeric SMILES: CC(C)(C)OC(=O)N1C[C@@H](C[C@H]1C(=O)O)O.C1CCC(CC1)NC2CCCCC2
• Uses: Dicyclohexylamine trans-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate is used in preparation of Pleuromutilin Alkoxycarbonyl Carbamate derivatives as antibacterial agents.

Technology Process of Dicyclohexylamine trans-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate

There total 1 articles about Dicyclohexylamine trans-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester; compound with dicyclohexyl-amine (21157-12-0)

Guidance literature:

Dicyclohexylamin, entspr. Aminosaeure;

DOI:10.1007/BF00565050