Mefluidide

Base Information

• Chemical Name: Mefluidide
• CAS No.: 53780-34-0
• Deprecated CAS: 55584-91-3,55599-99-0,55599-99-0
• Molecular Formula: C11H13 F3 N2 O3 S
• Molecular Weight: 310.297
• Hs Code.: 29350090
• European Community (EC) Number: 258-767-4
• UNII: 499DH82Q8O
• DSSTox Substance ID: DTXSID7034709
• Nikkaji Number: J1.900C
• Wikidata: Q22808361
• Mol file: 53780-34-0.mol

Synonyms:Mefluidide;N-(2,4-dimethyl-5-(((trifluoromethyl)sulfonyl)amino)phenyl)acetamide

Chemical Property of Mefluidide

Chemical Property:

• Melting Point: 183-185°
• PKA: 4.6(at 25℃)
• PSA: 83.65000
• Density: 1.3673 (estimate)
• LogP: 3.75010
• Water Solubility.: 0.18g/L(23 oC)
• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 3
• Exact Mass: 310.05989794
• Heavy Atom Count: 20
• Complexity: 459

Purity/Quality:

99%, ^*data from raw suppliers

Mefluidide analytical standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Pesticides -> Plant Growth Regulators
• Canonical SMILES: CC1=CC(=C(C=C1NC(=O)C)NS(=O)(=O)C(F)(F)F)C
• Uses: Plant growth regulator; herbicide. Plant growth regulator and herbicide used in lawns, turf, grassland, industrial areas and areas where grass cutting is difficult such as embankments. Also used to enhance sucrose content in sugarcane. Mefluidide is a plant growth regulator that suppresses annual bluegrass seedheads on creeping bentgrass greens. An antiparasitic agent.

Technology Process of Mefluidide

There total 3 articles about Mefluidide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Trifluoromethanesulfonyl fluoride (335-05-7) + 5-amino-2,4-dimethylacetanilide (53780-33-9) + ethyl acetate (141-78-6) + trimethylamine (75-50-3) → N-[2,4-dimethyl-5-[[(trifluoromethyl)sulfonyl]amino]phenyl]acetamide (53780-34-0)

Guidance literature:

24 h, 10 % NaOH soln.;

Reference yield:

5-amino-2,4-dimethyltrifluoromethylsulfonylaniline (53823-46-4) + acetic anhydride (108-24-7) → N-[2,4-dimethyl-5-[[(trifluoromethyl)sulfonyl]amino]phenyl]acetamide (53780-34-0)

Guidance literature:

In dichloromethane; at 10 ℃; for 1.75h; Reflux;

Reference yield:

→ N-[2,4-dimethyl-5-[[(trifluoromethyl)sulfonyl]amino]phenyl]acetamide (53780-34-0)

Guidance literature:

upstream raw materials:

Trifluoromethanesulfonyl fluoride

5-amino-2,4-dimethylacetanilide

ethyl acetate

trimethylamine

Refernces

• 1、 -. "Substituted pyridinesulfonamide compounds or their salts, process for preparing the same, and herbicides containing the same". . . Retrieved 2008/06/13.
• 2、 -. "Inhibiting grass growth with 5-acetamido-2,4-dimethyltrifluoromethanesulfonanilide". . . Retrieved 2008/06/13.