5-aminopentanesulfonic acid

Base Information

• Chemical Name: 5-aminopentanesulfonic acid
• CAS No.: 37043-68-8
• Molecular Formula: C5H13 N O3 S
• Molecular Weight: 167.229
• Mol file: 37043-68-8.mol

Synonyms:5-Amino-1-pentanesulfonicacid; 5-Aminopentanesulfonic acid; NSC 637821

Chemical Property of 5-aminopentanesulfonic acid

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 88.77000
• Density: 1.254g/cm³
• LogP: 1.78430

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-aminopentanesulfonic acid

There total 6 articles about 5-aminopentanesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

N-(5-bromopentyl)phthalimide (954-81-4) → 5-aminopentanesulfonic acid (37043-68-8)

Guidance literature:

N-(5-bromopentyl)phthalimide; With sodium sulfite; In ethanol; water; at 95 ℃; for 18h;

With hydrogenchloride; In water; at 110 ℃; for 18h;

Reference yield:

1,5-dibromo-pentane (111-24-0) → 5-aminopentanesulfonic acid (37043-68-8)

Guidance literature:

Multistep reaction; (i) aq. Na₂SO₃, EtOH, (ii) NH₄Cl;

DOI:10.1021/jm00239a013

Reference yield:

N-(5-chloropentyl)benzamide (74098-30-9) → 5-aminopentanesulfonic acid (37043-68-8)

Guidance literature:

With water; sodium sulfite; anschliessend Hydrolyse des Reaktionsprodukts mit NaOH;

upstream raw materials:

N-(5-chloropentyl)benzamide

1,5-dibromo-pentane

N-benzoylpiperidine

N-(5-bromopentyl)phthalimide

Downstream raw materials:

C₃₅H₃₅NO₁₁S

ε-Guanidinopentanesulfonic Acid

Refernces

• 1、 Deng, Hong,Liu, Xin,Xie, Jie,Yin, Rong,Huang, Naiyan,Gu, Ying,Zhao, Jingquan. "Quantitative and site-directed chemical modification of hypocrellins toward direct drug delivery and effective photodynamic activity". experimental part. p. 1910 - 1919. Retrieved 2012/05/20.
• 2、 Fujii,Cook. "Probiotics. Antistaphylococcal and antifibrinolytic activities of omega amino and omega guanidinoalkanesulfonic acids". . p. 502 - 505. Retrieved 2007/10/05.