Technology Process of TRANS-CYCLOBUTANE-1,2-DICARBOXAMIDE
There total 6 articles about TRANS-CYCLOBUTANE-1,2-DICARBOXAMIDE which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogen chloride; methanol
2: aqueous ammonia
With
hydrogenchloride; methanol; ammonium hydroxide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium chloride; methanol / 40 - 45 °C / Inert atmosphere
1.2: 20 °C
2.1: thionyl chloride / toluene / 14 h / 20 - 90 °C / Inert atmosphere
2.2: 10 °C / Inert atmosphere
With
methanol; thionyl chloride; lithium chloride;
In
toluene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 5,5-dibromohydantoin / dichloromethane / -10 - 20 °C / Inert atmosphere
2.1: potassium carbonate / N,N-dimethyl-formamide / 20 - 30 °C
3.1: lithium chloride; methanol / 40 - 45 °C / Inert atmosphere
3.2: 20 °C
4.1: thionyl chloride / toluene / 14 h / 20 - 90 °C / Inert atmosphere
4.2: 10 °C / Inert atmosphere
With
methanol; thionyl chloride; 5,5-dibromohydantoin; potassium carbonate; lithium chloride;
In
dichloromethane; N,N-dimethyl-formamide; toluene;
