Naphthalene, 1-(2-methoxyphenyl)-

Base Information

• Chemical Name: Naphthalene, 1-(2-methoxyphenyl)-
• CAS No.: 93321-11-0
• Molecular Formula: C17H14O
• Molecular Weight: 234.298
• Mol file: 93321-11-0.mol

Synonyms:

Chemical Property of Naphthalene, 1-(2-methoxyphenyl)-

Chemical Property:

• PSA: 9.23000
• LogP: 4.51540

Purity/Quality:

1-(2-Methoxyphenyl)naphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Naphthalene, 1-(2-methoxyphenyl)-

There total 45 articles about Naphthalene, 1-(2-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-Methoxyphenylboronic acid (5720-06-9) + 1-Chloronaphthalene (90-13-1) → 1-(2-methoxyphenyl)naphthalene (93321-11-0)

Guidance literature:

With potassium phosphate; C₅₀H₆₃Cl₂N₃Pd; In ethanol; at 80 ℃; for 4h;

DOI:10.1021/acs.organomet.6b00723

Reference yield: 95.0%

2-Chloroanisole (766-51-8) + 1-Naphthylboronic acid (13922-41-3) → 1-(2-methoxyphenyl)naphthalene (93321-11-0)

Guidance literature:

With (SC₈H₄C(CF₃)NC₆H₄OCH₃)PdCl(tricyclohexylphosphine)2; caesium carbonate; In 1,4-dioxane; at 100 ℃; Inert atmosphere;

DOI:10.1039/b927367k

Reference yield: 94.0%

1-naphthyl tosylate (68211-49-4) + 2-methoxyphenylmagnesium bromide (16750-63-3) → 1-(2-methoxyphenyl)naphthalene (93321-11-0)

Guidance literature:

2-methoxyphenylmagnesium bromide; With C₂₄H₅₂Cl₂O₁₂P₄Pd₂; In tetrahydrofuran; 1,4-dioxane; at 20 ℃; for 0.0833333h; Inert atmosphere;

1-naphthyl tosylate; In tetrahydrofuran; 1,4-dioxane; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1002/chem.201002386

upstream raw materials:

4-iodoanisol

1-Iodonaphthalene

2-(1-naphthyl)-2-cyclohexenone

2-(3,4-dihydro-[1]naphthyl)-anisole

Downstream raw materials:

benzo[a]fluorene

2,3-Benzo-fluoren

1-(2′-hydroxyphenyl)naphthalene

benzo[b]naphtho[1,8-de]pyran

Refernces

• 1、 Tang, Huiling,Liu, Mengna,Zhu, Meiqi,Cui, Benqiang,Shi, Yanhui,Cao, Changsheng. "C(sp2)-C(sp2) Suzuki cross-coupling of arylammonium salts catalyzed by a stable Pd–NHC complex". . . Retrieved 2021/09/15.
• 2、 Elaieb, Fethi,Sémeril, David,Matt, Dominique. "Resorcinarene-Based o-Biarylphosphines in Palladium-Catalysed Suzuki–Miyaura Cross-Coupling Reactions of Bulky Substrates". supporting information. p. 685 - 693. Retrieved 2017/02/05.