Iriflophene

Base Information

• Chemical Name: Iriflophene
• CAS No.: 52591-10-3
• Molecular Formula: C13H10O5
• Molecular Weight: 246.219
• Hs Code.: 2914501900
• Mol file: 52591-10-3.mol

Synonyms:Methanone, (4-hydroxyphenyl)(2,4,6-trihydroxyphenyl)-;

Chemical Property of Iriflophene

Chemical Property:

• Melting Point: 210 °C
• Boiling Point: 482.4±33.0 °C(Predicted)
• PKA: 7.03±0.40(Predicted)
• PSA: 97.99000
• Density: 1.526±0.06 g/cm3(Predicted)
• LogP: 1.74000

Purity/Quality:

98%Min ^*data from raw suppliers

Iriflophenone 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Iriflophene

There total 2 articles about Iriflophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4',6-trihydroxybenzophenone 2-O-α-L-rhamnopyranoside (943989-68-2) → 4,2',4',6'-tetrahydroxybenzophenone (52591-10-3)

Guidance literature:

With sulfuric acid; for 2h; Heating;

DOI:10.1271/bbb.70361

Reference yield:

3,5-dihydroxyphenol (108-73-6) + 4-cyanophenol (767-00-0) → 4,2',4',6'-tetrahydroxybenzophenone (52591-10-3)

Guidance literature:

With hydrogenchloride; diethyl ether; zinc(II) chloride; Versetzen des Reaktionsgemisches mit 25prozentiger Schwefelsaeure und Kochen des in gelben Nadeln krystallisierenden Imidsulfats mit Wasser;

Reference yield: 100.0%

UDP-glucose (133-89-1) + 4,2',4',6'-tetrahydroxybenzophenone (52591-10-3) → 2,4,4',6-tetrahydroxy benzophenone-3-C-β-D-glucoside (104669-02-5)

Guidance literature:

With C-glycosyltransferase from Mangifera indica; In methanol; at 40 ℃; for 12h; pH=6.6; Enzymatic reaction;

DOI:10.1002/chem.201600411

upstream raw materials:

3,5-dihydroxyphenol

4-cyanophenol

4,4',6-trihydroxybenzophenone 2-O-α-L-rhamnopyranoside

Downstream raw materials:

2,4,4',6-tetrahydroxy benzophenone-3-C-β-D-glucoside

Refernces

• 1、 Rancon, Sandrine,Chaboud, Annie,Darbour, Nicole,Comte, Gilles,Bayet, Christine,Simon, Pierre-Noel,Raynaud, Jean,Di Pietro, Attilio,Cabalion, Pierre,Barron, Denis. "Natural and synthetic benzophenones: Interaction with the cytosolic binding domain of P-glycoprotein". . p. 553 - 557. Retrieved 2001.