2-(4-Methoxybenzyl)succinic acid

Base Information

• Chemical Name: 2-(4-Methoxybenzyl)succinic acid
• CAS No.: 956-41-2
• Molecular Formula: C12H14O5
• Molecular Weight: 238.24
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID70385518
• Mol file: 956-41-2.mol

Synonyms:2-(4-methoxybenzyl)succinic acid;956-41-2;2-[(4-methoxyphenyl)methyl]butanedioic acid;2-(4-methoxybenzyl)butanedioic acid;2-(4-Methoxybenzyl)succinicacid;2-(4-Methoxy-benzyl)-succinic acid;ChemDiv3_002891;Oprea1_196648;Oprea1_400045;SCHEMBL6178867;DTXSID70385518;HMS1481D09;BBL028788;STK722170;AKOS000620371;AKOS016844092;CCG-103998;VS-08970;CS-0318967;3-(p-methoxyphenyl)-1 ,2-propanedicarboxylic;SR-01000485914;SR-01000485914-1

Chemical Property of 2-(4-Methoxybenzyl)succinic acid

Chemical Property:

• PSA: 83.83000
• LogP: 1.41320
• Storage Temp.: 2-8°C
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 238.08412354
• Heavy Atom Count: 17
• Complexity: 268

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Methoxybenzyl)succinicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)CC(CC(=O)O)C(=O)O

Technology Process of 2-(4-Methoxybenzyl)succinic acid

There total 15 articles about 2-(4-Methoxybenzyl)succinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-methoxy-benzyl)-trimethyl-silane (17988-20-4) + maleic acid (110-16-7,26099-09-2) → 1,2-bis(4-methoxyphenyl)ethane (1657-55-2) + (4-methoxy-benzyl)-succinic acid (956-41-2) + 4-methoxy-benzaldehyde (123-11-5) + 2-(4-Methoxy-benzyl)-3-(4-methoxy-cyclohexa-1,5-dienylmethyl)-succinic acid

Guidance literature:

With titanium(IV) oxide; In acetonitrile; for 20h; Product distribution; Irradiation; other reaction time, reaction conditions;

DOI:10.1016/S0040-4020(98)00020-9

Reference yield:

4-Methoxyphenylacetic acid (104-01-8) + maleic acid (110-16-7,26099-09-2) + 1,2-Dicyanoethylene (764-42-1) → 1,2-bis(4-methoxyphenyl)ethane (1657-55-2) + (4-methoxy-benzyl)-succinic acid (956-41-2) + 4-methoxy-benzaldehyde (123-11-5)

Guidance literature:

With titanium(IV) oxide; In acetonitrile; for 20h; Product distribution; Irradiation; other reaction time;

DOI:10.1016/S0040-4020(98)00020-9

Reference yield:

((E)-4-methoxy-benzylidene)-succinic acid (15889-58-4) → (4-methoxy-benzyl)-succinic acid (956-41-2)

Guidance literature:

With methanol; palladium on activated charcoal; Hydrogenation;

upstream raw materials:

p-methylanizole

2,4-oxetanedione

3-(4-methoxy-phenyl)-propane-1,2,2-tricarboxylic acid triethyl ester

((E)-4-methoxy-benzylidene)-succinic acid

Downstream raw materials:

6β,6'β-[(Ξ)-2-(4-methoxy-benzyl)-succinyldiamino]-bis-penicillanic acid

(4-methoxy-benzyl)-succinic acid anhydride

Refernces

• 1、 Cermenati, Laura,Richter, Christoph,Albini, Angelo. "Solar light induced carbon-carbon bond formation via TiO2 photocatalysis". . p. 805 - 806. Retrieved 2007/10/03.