Technology Process of (2S,3R)-2,5-Dihydroxy-3-methylpentanoic acid
There total 8 articles about (2S,3R)-2,5-Dihydroxy-3-methylpentanoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: H2 / PtO2 / ethyl acetate / 5 h / 2206.5 Torr / Ambient temperature
2: conc.HCl / methanol / Ambient temperature
3: 49 percent / CrO3, H2SO4 / acetone / 1 h
4: LiBH4 / tetrahydrofuran / 6 h / Heating
With
chromium(VI) oxide; hydrogenchloride; lithium borohydride; sulfuric acid; hydrogen;
platinum(IV) oxide;
In
tetrahydrofuran; methanol; ethyl acetate; acetone;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: NaIO4, 18-crown-6 / H2O; ethyl acetate / 60 °C
2: diethyl ether; tetrahydrofuran / 48 h / Ambient temperature
3: 92 percent / dioxane / 50 h / Heating
4: H2 / PtO2 / ethyl acetate / 5 h / 2206.5 Torr / Ambient temperature
5: conc.HCl / methanol / Ambient temperature
6: 49 percent / CrO3, H2SO4 / acetone / 1 h
7: LiBH4 / tetrahydrofuran / 6 h / Heating
With
chromium(VI) oxide; hydrogenchloride; sodium periodate; lithium borohydride; 18-crown-6 ether; sulfuric acid; hydrogen;
platinum(IV) oxide;
In
tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; water; ethyl acetate; acetone;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: diethyl ether; tetrahydrofuran / 48 h / Ambient temperature
2: 92 percent / dioxane / 50 h / Heating
3: H2 / PtO2 / ethyl acetate / 5 h / 2206.5 Torr / Ambient temperature
4: conc.HCl / methanol / Ambient temperature
5: 49 percent / CrO3, H2SO4 / acetone / 1 h
6: LiBH4 / tetrahydrofuran / 6 h / Heating
With
chromium(VI) oxide; hydrogenchloride; lithium borohydride; sulfuric acid; hydrogen;
platinum(IV) oxide;
In
tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; ethyl acetate; acetone;