1,4-Bis(4-bromophenyl)buta-1,3-diyne

Base Information

• Chemical Name: 1,4-Bis(4-bromophenyl)buta-1,3-diyne
• CAS No.: 959-88-6
• Molecular Formula: C16H8Br2
• Molecular Weight: 360.048
• Mol file: 959-88-6.mol

Synonyms:1,1'-buta-1,3-diyne-1,4-diylbis(4-bromobenzene);1,4-bis(4-bromophenyl)buta-1,3-diyne;1,4-bis(4-bromodiphenyl)buta-1,3-diyne;1,4-bis<4-bromophenyl>-1,3-butadiyne;1-Bromo-4-[4-(4-bromophenyl)-1,3-butadiynyl]benzene;B4013;bis(p-bromophenyl)butadiine;bis-(4-bromo-phenyl)-butadiyne;1,3-Butadiyne,1,4-di(4-bromophenyl);

Chemical Property of 1,4-Bis(4-bromophenyl)buta-1,3-diyne

Chemical Property:

• Melting Point: 265 °C(dec.)
• PSA: 0.00000
• LogP: 4.61480

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,4-Bis(4-bromophenyl)-1,3-butadiyne >98.0%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,4-Bis(4-bromophenyl)buta-1,3-diyne

There total 17 articles about 1,4-Bis(4-bromophenyl)buta-1,3-diyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-bromo-1-ethynylbenzene (766-96-1) → 1,4-bis(4-bromodiphenyl)buta-1,3-diyne (959-88-6)

Guidance literature:

With copper(l) iodide; nickel(II) chloride hexahydrate; N,N,N,N,-tetramethylethylenediamine; oxygen; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/ol8027863

Reference yield: 89.0%

3-(4-bromophenyl)-2-propynoic acid (25294-65-9) → 1,4-bis(4-bromodiphenyl)buta-1,3-diyne (959-88-6)

Guidance literature:

With copper(l) iodide; iodine; potassium carbonate; In dimethyl sulfoxide; at 50 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tet.2014.02.022

Reference yield: 85.0%

4-bromo-1-ethynylbenzene (766-96-1) + acetophenone oxime (613-91-2) + acetic anhydride (108-24-7) → 1,4-bis(4-bromodiphenyl)buta-1,3-diyne (959-88-6) + N-(1-phenylvinyl)acetamide (57957-24-1)

Guidance literature:

With pyridine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In 1,2-dichloro-ethane; at 120 ℃; for 5h; Inert atmosphere; Green chemistry;

DOI:10.1016/S1872-2067(14)60220-5

upstream raw materials:

4-bromo-1-ethynylbenzene

hydrogenchloride

methyl ester of N-(tert-butoxycarbonyl)-β,β-dibromodehydroalanine

formaldehyd

Downstream raw materials:

2,5-Bis(p-bromophenyl)thiophene

2,5-bis(4-bromophenyl)-3-(triisopropylsilyl)thiophene

3,6-bis(4-bromophenyl)-[1,2]dithiolo[4,3-c][1,2]dithiole

ethyl 1-p-benzoate-2,5-di-p-bromopyrrole

Refernces

• 1、 Liu, Guogang,Chen, Didi,Kong, Lingwei,Shi, Jianbing,Tong, Bin,Zhi, Junge,Feng, Xiao,Dong, Yuping. "Red fluorescent luminogen from pyrrole derivatives with aggregation-enhanced emission for cell membrane imaging". . p. 8555 - 8558. Retrieved 2015.
• 2、 -. "AIE compound, preparation method and application in detection of organic amine". Paragraph 0110-0112; 0116-0117. . Retrieved 2021/06/23.
• 3、 Kaldhi, Dhananjaya,Vodnala, Nagaraju,Gujjarappa, Raghuram,Kabi, Arup K.,Nayak, Subhashree,Malakar, Chandi C.. "Transition-metal-free variant of Glaser- and Cadiot-Chodkiewicz-type Coupling: Benign access to diverse 1,3-diynes and related molecules". supporting information. . Retrieved 2020/03/13.