7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid

Base Information Edit

Chemical Name:7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid
CAS No.:877674-77-6
Molecular Formula:C13H20ClNO3
Molecular Weight:273.76
Hs Code.:
European Community (EC) Number:618-065-4
DSSTox Substance ID:DTXSID401133662
Mol file:877674-77-6.mol

Synonyms:877674-77-6;7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid;(S,Z)-7-Chloro-2-(2,2-dimethylcyclopropanecarboxamido)hept-2-enoic acid;7-chloro-2-((((1s)-2,2-dimethylcyclopropyl)carbonyl)amino)-2-heptenoic acid;SCHEMBL278792;(2Z)-7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid;DTXSID401133662;AKOS015904234;J-519190;(S,Z)-7-chloro-2-(2,2-dimethylcyclopropane-1-carboxamido)hept-2-enoic acid;(Z)-7-chloro-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid;(2Z)?-7-?Chloro-?2-?[[[(1S)?-?2,?2-?dimethylcyclopropyl]?carbonyl]?amino]?-?2-?heptenoic Acid

Suppliers and Price of 7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2Z)?-7-?Chloro-?2-?[[[(1S)?-?2,?2-?dimethylcyclopropyl]?carbonyl]?amino]?-?2-?heptenoicAcid
5g
$ 180.00

TRC
(2Z)?-7-?Chloro-?2-?[[[(1S)?-?2,?2-?dimethylcyclopropyl]?carbonyl]?amino]?-?2-?heptenoicAcid
1g
$ 80.00

Medical Isotopes, Inc.
(2Z)-7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoicAcid
5 g
$ 575.00

Medical Isotopes, Inc.
(2Z)-7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoicAcid
1 g
$ 375.00

Total 45 raw suppliers

Chemical Property of 7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid Edit

Chemical Property:

Boiling Point:504.547 °C at 760 mmHg
Flash Point:258.941 °C
PSA：69.89000
Density:1.189 g/cm³
LogP:3.36660
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:273.1131712
Heavy Atom Count:18
Complexity:363

Purity/Quality:

98% ^*data from raw suppliers

(2Z)?-7-?Chloro-?2-?[[[(1S)?-?2,?2-?dimethylcyclopropyl]?carbonyl]?amino]?-?2-?heptenoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC1C(=O)NC(=CCCCCCl)C(=O)O)C
Isomeric SMILES:CC1(C[C@@H]1C(=O)N/C(=C\CCCCCl)/C(=O)O)C
Uses (2Z)?-7-?Chloro-?2-?[[[(1S)?-?2,?2-?dimethylcyclopropyl]?carbonyl]?amino]?-?2-?heptenoic Acid is a reagent used in the preparation of Cilastatin (C441105), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.

Technology Process of 7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid

There total 11 articles about 7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%