Sensorcaine

Base Information

• Chemical Name: Sensorcaine
• CAS No.: 73360-54-0
• Molecular Formula: C₁₈H₂₈N₂O*ClH*H₂O
• Molecular Weight: 342.909
• European Community (EC) Number: 642-205-3
• UNII: 7TQO7W3VT8
• DSSTox Substance ID: DTXSID501323779
• Wikidata: Q27887879
• NCI Thesaurus Code: C28876
• RXCUI: 267396
• Mol file: 73360-54-0.mol

Synonyms:1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide;Bupivacain Janapharm;Bupivacain RPR;Bupivacain-RPR;Bupivacaina Braun;Bupivacaine;Bupivacaine Anhydrous;Bupivacaine Carbonate;Bupivacaine Hydrochloride;Bupivacaine Monohydrochloride, Monohydrate;Buvacaina;Carbostesin;Dolanaest;Marcain;Marcaine;Sensorcaine;Svedocain Sin Vasoconstr

Chemical Property of Sensorcaine

Chemical Property:

• Melting Point: 255-259℃
• PSA: 45.06000
• LogP: 5.22160
• Storage Temp.: room temp
• Water Solubility.: Soluble in water to 50 mM, in DMSO to 100 mM and in ethanol to 100 mM.
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 342.2074059
• Heavy Atom Count: 23
• Complexity: 321

Purity/Quality:

99% ^*data from raw suppliers

Bupivacaine hydrochloride monohydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T+
• Hazard Codes: T+
• Statements: 26/27/28
• Safety Statements: 22-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl
• Recent ClinicalTrials: Phase 3 Study of Efficacy and Safety of the XaraColl? Bupivacaine Implant After Hernioplasty
• Uses: It is employed as Na+ channel blocker, local anesthetic and cAMP production inhibitor. It acts as a surfactant molecule possessing both hydrophilic and lipophilic properties, adrenergic antagonist, EC 3.1.1.8 (cholinesterase) inhibitor and EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor.

Technology Process of Sensorcaine

There total 1 articles about Sensorcaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ bupivacaine hydrochloride monohydrate (73360-54-0)

Guidance literature:

Refernces

• 1、 -. "Racemisation process for use in the manufacture of levobupivacaine and related piperidinecarboxanilide anaesthetic agents". . . Retrieved 2008/06/13.