2-Bromo-1,3,4,5-tetrafluorobenzene

Base Information

• Chemical Name: 2-Bromo-1,3,4,5-tetrafluorobenzene
• CAS No.: 1559-86-0
• Molecular Formula: C6H Br F4
• Molecular Weight: 228.972
• Hs Code.: 2903999090
• European Community (EC) Number: 216-325-8
• UNII: RB2PYS9NWB
• DSSTox Substance ID: DTXSID00165986
• Nikkaji Number: J206.788I
• Wikidata: Q72505112
• Mol file: 1559-86-0.mol

Synonyms:1559-86-0;2-Bromo-1,3,4,5-tetrafluorobenzene;1-Bromo-2,3,4,6-tetrafluorobenzene;Benzene, 2-bromo-1,3,4,5-tetrafluoro-;EINECS 216-325-8;2,3,4,6-Tetrafluoro bromobenzene;1,2,3,5-tetrafluoro-4-bromobenzene;RB2PYS9NWB;SCHEMBL2933659;DTXSID00165986;AKOS024319317;2-Bromo-1,3,4,5-tetrafluorobenzene #;A809706

Chemical Property of 2-Bromo-1,3,4,5-tetrafluorobenzene

Chemical Property:

• Vapor Pressure: 8.02mmHg at 25°C
• Boiling Point: 139.4°Cat760mmHg
• Flash Point: 48°C
• PSA: 0.00000
• Density: 1.869g/cm³
• LogP: 3.00550
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 227.91978
• Heavy Atom Count: 11
• Complexity: 143

Purity/Quality:

98%min ^*data from raw suppliers

2,3,4,6-TETRAFLUOROBROMOBENZENE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=C(C(=C(C(=C1F)Br)F)F)F

Technology Process of 2-Bromo-1,3,4,5-tetrafluorobenzene

There total 3 articles about 2-Bromo-1,3,4,5-tetrafluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-dibromo-2,4,5,6-tetrafluorobenzene (1559-87-1) → 2-bromo-1,3,4,5-tetrafluorobenzene (1559-86-0) + 1,2,3,5-tetrafluorobenzene (2367-82-0)

Guidance literature:

With water; hexaethylphosphoric triamide; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

DOI:10.1007/BF02495214

Reference yield:

1,2,3,5-tetrafluorobenzene (2367-82-0) → 2-bromo-1,3,4,5-tetrafluorobenzene (1559-86-0)

Guidance literature:

Multistep reaction; (i) Br₂, AlBr₃, SO₃/H₂SO₄, (ii) Zn, AcOH;

DOI:10.1016/S0040-4020(01)99045-3

Reference yield:

→ 2-bromo-1,3,4,5-tetrafluorobenzene (1559-86-0)

Guidance literature:

1,3-Dibromtetrafluorbenzol + Zn/HOAc, Δ;

upstream raw materials:

1,2,3,5-tetrafluorobenzene

1,3-dibromo-2,4,5,6-tetrafluorobenzene

Downstream raw materials:

1,3-dibromo-2,4,5,6-tetrafluorobenzene

1-bromo-2,3,4,6-trafluoro-5-iodobenzene

1,2,3,5-tetrafluorobenzene

2,2',3,3',4,4',6,6'-octafluorobiphenyl

Refernces

• 1、 Bardin,Pressman. "Reaction of polyfluoroaromatic compounds with electrophilic agents in the presence of tris(dialkylamino)phosphines: 7. * Replacement of a halogen by hydrogen in halogenopolyfluoroaromatic compounds". . p. 786 - 788. Retrieved 2007/10/03.