2-[Bis(carboxymethyl)amino]glutaric acid

Base Information

• Chemical Name: 2-[Bis(carboxymethyl)amino]glutaric acid
• CAS No.: 58976-65-1
• Deprecated CAS: 1309795-47-8,251579-26-7
• Molecular Formula: C9H13 N O8
• Molecular Weight: 263.204
• European Community (EC) Number: 261-530-8
• DSSTox Substance ID: DTXSID70860638
• Nikkaji Number: J3.068.587C
• Mol file: 58976-65-1.mol

Synonyms:GLDA chelating agent;N,N-bis(carboxymethyl)glutamic acid

Chemical Property of 2-[Bis(carboxymethyl)amino]glutaric acid

Chemical Property:

• Vapor Pressure: 2.64E-15mmHg at 25°C
• Boiling Point: 587.1°C at 760 mmHg
• Flash Point: 308.9°C
• PSA: 152.44000
• Density: 1.612g/cm³
• LogP: -1.22440
• Water Solubility.: 291g/L at 20℃
• XLogP3: -3.3
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 9
• Exact Mass: 263.06411637
• Heavy Atom Count: 18
• Complexity: 337

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(=O)O)C(C(=O)O)N(CC(=O)O)CC(=O)O

Technology Process of 2-[Bis(carboxymethyl)amino]glutaric acid

There total 13 articles about 2-[Bis(carboxymethyl)amino]glutaric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + hydrogen cyanide (74-90-8) + L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) → glutamic acid monoacetic acid (45084-14-8) + L-glutamic acid N,N-diacetic acid (58976-65-1)

Guidance literature:

formaldehyd; hydrogen cyanide; L-glutamic acid; With sodium hydroxide; In water; at 90 - 105 ℃; for 4h;

With sulfuric acid; In water; at 33 ℃; pH=1.8;

Reference yield:

L-glutamic acid N,N-diacetic acid tetra sodium salt → L-glutamic acid N,N-diacetic acid (58976-65-1)

Guidance literature:

In water; at 40 ℃; Inert atmosphere; Electrochemical reaction;

Reference yield:

L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + bromoacetic acid (79-08-3) → L-glutamic acid N,N-diacetic acid (58976-65-1) + L-N-(carboxymethyl)glutamic acid (41035-85-2)

Guidance literature:

With water; magnesium oxide;

upstream raw materials:

L-glutamic acid

bromoacetic acid

chloroacetic acid

formaldehyd

Downstream raw materials:

D,L-GLDA-KH₃

Refernces

• 1、 -. "CRYSTALLINE PARTICLES OF SALTS OF GLUTAMIC ACID N,N-DIACETIC ACID". Page/Page column 17-18. . Retrieved 2014/07/07.
• 2、 -. "PROCESS TO PREPARE AMINO ACID-N, N-DIACETIC ACID COMPOUNDS". Page/Page column 16-19; 1/1. . Retrieved 2008/12/06.