daphnoretin

Base Information

• Chemical Name: daphnoretin
• CAS No.: 2034-69-7
• Molecular Formula: C19H12O7
• Molecular Weight: 352.3
• Mol file: 2034-69-7.mol

Synonyms:Coumarin,7-hydroxy-6-methoxy-3,7'-oxydi- (7CI,8CI);Daphnoretin;NSC 291852;Thymelol;

Chemical Property of daphnoretin

Chemical Property:

• Vapor Pressure: 5.92E-17mmHg at 25°C
• Melting Point: 245-246℃
• Refractive Index: 1.674
• Boiling Point: 639.6 °C at 760 mmHg
• PKA: 7.53±0.20(Predicted)
• Flash Point: 237.8 °C
• Density: 1.501 g/cm³
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Daphnoretin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Daphnoretin is an active constituent of Wikstroemia indica C. A. Meys which possesses anti-cancer activity. Inhibitory effect on mitosis.

Technology Process of daphnoretin

There total 1 articles about daphnoretin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chamaejasmoside → D-Galactose (10257-28-0) + daphnoretin (2034-69-7)

Guidance literature:

With sulfuric acid; for 4h; Heating;

DOI:10.1007/BF00630004

Reference yield: 75.0%

daphnoretin (2034-69-7) + acetic anhydride (108-24-7) → 7-O-acetyl daphnoretin (17064-09-4)

Guidance literature:

In pyridine; at 100 ℃; for 6h;

DOI:10.1016/S0031-9422(00)85530-2

Reference yield:

1,4-dibromo-butane (110-52-1) + daphnoretin (2034-69-7) + sodium t-butanolate (865-48-5) → 7-(4-tert-butoxy)butyldaphnoretin

Guidance literature:

1,4-dibromo-butane; daphnoretin; With potassium carbonate; potassium iodide; In butanone; Reflux;

sodium t-butanolate; With potassium carbonate; In tetrahydrofuran; at 20 ℃; for 5h;

Downstream raw materials:

7-O-acetyl daphnoretin

Daphnoretin methyl ether

Refernces